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Parecoxib

Parecoxib Structure
Parecoxib
  • CAS No.198470-84-7
  • Chemical Name:Parecoxib
  • CBNumber:CB81515695
  • Molecular Formula:C19H18N2O4S
  • Formula Weight:370.42
  • MOL File:198470-84-7.mol
Parecoxib Property
  • Melting point 148.9-151°
  • Density 1.264
  • storage temp. 2-8°C
  • solubility DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka 5.08±0.10(Predicted)
  • color White to off-white
  • BRN 8640266
  • FDA UNII 9TUW81Y3CE
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H361fd-H373
  • Precautionary statements P201-P202-P260-P280-P308+P313-P405
Parecoxib Price More Price(4)
  • Brand: Sigma-Aldrich
  • Product number: 32152
  • Product name : Parecoxib
  • Purity: VETRANAL?, analytical standard
  • Packaging: 25MG
  • Price: ₹19171.08
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 32152
  • Product name : Parecoxib
  • Purity: VETRANAL?, analytical standard
  • Packaging: 25MG
  • Price: ₹19171.08
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: P2579
  • Product name : Parecoxib
  • Purity: 
  • Packaging: 50MG
  • Price: ₹4200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: P2579
  • Product name : Parecoxib
  • Purity: 
  • Packaging: 250MG
  • Price: ₹9800
  • Updated: 2022/05/26
  • Buy: Buy

Parecoxib Chemical Properties,Usage,Production

  • Uses Anti-inflammatory; analgesic (cyclooxygenase COX-2 inhibitor).
  • Uses Parecoxib is used in the combination with Telmisartan for the treatment of endometriosis. Parecoxib reduces hippocampal inflammation and improve short-term memory function through the inhibition of COX-2 expression in aged rats after splenectomy.
  • Definition ChEBI: An N-acylsulfonamide resulting from the formal condensation of valdecoxib with propionic acid. It is a prodrug for valdecoxib.
  • in vivo

    Parecoxib (intraperitoneal injection; 2.5, 5.0 or 10?mg/kg; once a day; 21?days) does not affect locomotor activity in the elevated plus-maze test, and Parecoxib at 5 and 10?mg/kg shows higher levels of percentage of time spent in the open arms[3].

    Animal Model:Naive adult male ICR mice, 15?weeks old and weighing 25-35?g[3]
    Dosage:2.5, 5.0 or 10?mg/kg
    Administration:Intraperitoneal injection; 2.5, 5.0 or 10?mg/kg; once a day; 21?days
    Result:Exerted an anxiolytic-like effect in the elevated plus-maze test
  • IC 50 COX-2
Parecoxib Preparation Products And Raw materials
Raw materials
Preparation Products
Parecoxib Suppliers
Global(223)Suppliers
  • Supplier：
    Hangzhou FandaChem Co.,Ltd.
  • Tel：008657128800458;<br/>+8615858145714
  • Email：FandaChem@Gmail.com
  • Country：China
  • ProdList：3608
  • Advantage：55
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29859
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
Parecoxib Spectrum
198470-84-7, ParecoxibRelated Search:
  • ZY
  • Inhibitors
  • 抑制剂
  • 生化试剂
  • 试剂
  • 医药体
  • 化学试剂
  • 医药化工类
  • 杂质对照品
  • 医药原料药-科研原料
  • 抗炎镇痛药物
  • 医药化工类
  • 医药原料
  • 对照品-杂质对照品
  • 小分子抑制剂
  • 小分子抑制剂，天然产物
  • 原料药
  • 医药中间体
  • 帕瑞昔布钠相关中间体
  • 医药,农药中间体
  • 帕瑞昔布钠中间体
  • 帕瑞昔布中间体
  • 帕瑞昔布,10 MM DMSO 溶液
  • 乙腈中帕瑞昔布
  • 代他考昔杂质1
  • 伐地考昔杂质38
  • 伐地昔布杂质J
  • N-[[4-(5-甲基-3-苯基-4-异恶唑基)苯基]磺酰基]丙酰胺(帕瑞昔布)
  • N-((4-(5-甲基-3-苯基异恶唑-4-基)苯基)磺酰基)丙酰胺
  • 帕瑞昔布PARECOXIB
  • 帕瑞考昔钠杂质81
  • 帕瑞昔布钠杂质81
  • 帕瑞昔布(游离)
  • 帕瑞昔布
  • 帕瑞昔布钠杂质J
  • 4-(5-甲基-3-苯基-异噁唑基)-N-丙酰基苯磺酰胺
  • 帕瑞昔布钠杂质 W
  • N-[[4-(5-甲基-3-苯基-4-异恶唑基)苯基]磺酰基]丙酰胺
  • N-[[4-(5-甲基-3-苯基-4-异恶唑基)苯基]磺酰基]丙酰胺盐
  • N-{[4-(5-甲基-3-苯基-4-异恶唑-4-基)苯基]磺酰基}丙酰胺
  • 帕瑞昔布钠杂质I
  • 帕瑞昔布钠杂质,PR-12-I
  • 198470-84-7
  • Parecoxib, 10 mM in DMSO
  • N-{[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonyl}propanamide
  • (3aR,4R,6S,6aS)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazole-6-carbox
  • Paricoxib
  • Valdecoxib Impurity 38
  • osteoarthritis,POCD,rheumatoid arthritis,pain,Cyclooxygenase,cognitive dysfunction,postoperative,Parecoxib,coxibs,analgesia,Inhibitor,inhibit,chronic inflammatory condition,SC69124,SC-69124,COX
  • N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanamide
  • Paris yesterday
  • Parecoxib D5
  • Parecoxib (SC 69124)
  • parecoxib free base
  • Parecoxib Sodium Impurity 81
  • Parecoxib impurities
  • Parecoxib USP/EP/BP
  • Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-

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