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5-Methyl-3,4-diphenylisoxazole

5-Methyl-3,4-diphenylisoxazole Structure
5-Methyl-3,4-diphenylisoxazole
  • CAS No.37928-17-9
  • Chemical Name:5-Methyl-3,4-diphenylisoxazole
  • CBNumber:CB52604537
  • Molecular Formula:C16H13NO
  • Formula Weight:235.28
  • MOL File:37928-17-9.mol
5-Methyl-3,4-diphenylisoxazole Property
  • Melting point 96.0 to 100.0 °C
  • Boiling point 340.1±21.0 °C(Predicted)
  • Density 1.108±0.06 g/cm3(Predicted)
  • storage temp. Sealed in dry,Room Temperature
  • solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka -2.53±0.50(Predicted)
  • color White to Off-White
  • InChIKey ZXIRUKJWLADSJS-UHFFFAOYSA-N
Safety
  • HS Code  :2934.99.4400
  • NFPA 704:
    1
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
5-Methyl-3,4-diphenylisoxazole Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: M2830
  • Product name : 5-Methyl-3,4-diphenylisoxazole
  • Purity: min. 98.0 %
  • Packaging: 1G
  • Price: ₹3200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: M2830
  • Product name : 5-Methyl-3,4-diphenylisoxazole
  • Purity: min. 98.0 %
  • Packaging: 5G
  • Price: ₹8200
  • Updated: 2022/05/26
  • Buy: Buy

5-Methyl-3,4-diphenylisoxazole Chemical Properties,Usage,Production

  • Uses 5-Methyl-3,4-diphenylisoxazole is a reagent for the preparation of valdecoxib and valdecoxib analogues.
  • Uses 5-Methyl-3,4-diphenylisoxazole is synthesis The key intermediate of Parecoxib Sodium (Parecoxib Sodium).Parecoxib Sodium is by the Pfizer of the U.S. The cox 2 inhibitor of company's research and development, listed in European Union in 2002, trade name Dynastat, is used for The short term therapy of postoperative pain.
  • Synthesis Synthesis_37928-17-9
    In four mouthfuls of round-bottomed flasks of a 1L add compound 2 (40g), methanol (400mL), 7.7% Aqueous sodium carbonate (400mL), is heated to 70 DEG C, after stirring reaction 2h, and TLC plate monitoring raw material Fundamental reaction is complete, and solution is divided into solid-liquid biphase, is extracted with ethyl acetate, collected organic layer, with anhydrous Sodium sulfate is dried, and vacuum obtains white solid, HPLC purity: 94.9% after being spin-dried for.White solid uses 40ml ethyl acetate and the mixed solvent recrystallization of 120ml normal hexane (1:3) again, Obtaining target compound is white solid 34.2g, yield 92%, HPLC purity: 99.7%.m.p.97-98??￡? MS(m/z):236(M+H)+￡?1H NMR(400MHz,CDCl3) |?:2.43(s,3H,-CH3), 7.19-7.43 (m, 10H ,-CH=).
5-Methyl-3,4-diphenylisoxazole Preparation Products And Raw materials
Raw materials
Preparation Products
5-Methyl-3,4-diphenylisoxazole Suppliers
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5-Methyl-3,4-diphenylisoxazole Spectrum
37928-17-9, 5-Methyl-3,4-diphenylisoxazoleRelated Search:
  • API
  • 医药
  • 抑制剂
  • 高端化学
  • 罗沙司他中间体
  • 中间体-中间体
  • 化学试剂
  • 苯环
  • 化工中间体
  • 杂质对照品
  • 对照品-杂质对照品
  • 标准品
  • 异恶唑
  • 中间体
  • 帕瑞昔布钠中间体
  • 医药中间体
  • 帕瑞昔布钠相关中间体
  • 帕瑞昔布中间体
  • 37928-19-7
  • 化合物 5-METHYL-3,4-DIPHENYLISOXAZOLE
  • 帕瑞考昔杂质9
  • 帕瑞昔布杂质19(脱硫酰胺)
  • 5-甲基-3,4-二苯基异恶唑5-METHYL-3,4-DIPHENYLISOXAZOLE
  • 帕瑞考昔钠杂质30
  • 帕瑞昔布脱硫酰胺杂质
  • 帕瑞昔布杂质1 全套杂质
  • 5-甲基-3
  • 4-二苯基异噁唑
  • 匹杉琼杂质9
  • 5-甲基-3,4-二苯基异F唑
  • 帕瑞昔布杂质19
  • 5-甲基-3,4-二苯基异噁唑 (帕瑞昔布钠中间体)
  • 5-甲基-3,4-二苯基异噁唑
  • 5-甲基-3,4-二苯基异恶唑 (帕瑞昔布钠中间体)
  • 5-甲基-3.4-二苯异恶唑
  • 5-甲基-3,4-二苯基异恶唑
  • 5-甲基-3,4-二苯基异唑
  • 3,4-二苯基-5-甲基异恶唑
  • 帕瑞西布纳中间体A
  • 5-甲基-3.4-二苯异恶唑(帕瑞昔布钠中间体)
  • 帕瑞昔布钠杂质05
  • 5-甲基-3,4-二苯基异噁唑 (帕瑞昔布钠中间体) 50G
  • 帕瑞昔布钠中间体 5-甲基-3,4-二苯基异噁唑
  • 帕瑞昔布钠杂质,PR-SM
  • 37928-17-9
  • Parecoxib Impurity 19 (Desulfonamide)
  • 5-Methyl-3,4-diphenyl
  • lsoxazole,5-Methyl-3,4-diphenyl-(Parecoxib sodiuM inteMediate)
  • Valdecoxib Impurity 10 (Desulfonamide)
  • 4-diphenyl-(Parecoxib sodiuM inteMediate)
  • 5-Methyl-3
  • Parecoxib impurity 5/5-methyl-3,4-diphenylisoxazole
  • Parecoxib Related Compound
  • Parecoxib Impurity 19 (Valdecoxib Impurity 10 (Desulfonamide))
  • Valdecoxib Impurity 10 (Desulfonamide) (Parecoxib Impurity 19)
  • Parecoxib Sodium-4
  • 5-Methyl-3,4-diphenyl-1,2-oxazole
  • PARECOXIB SODIUM CAS 198470-85-8 INTERMEDIATES

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