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L-Arginine L-glutamate

L-Arginine L-glutamate Structure
L-Arginine L-glutamate
  • CAS No.4320-30-3
  • Chemical Name:L-Arginine L-glutamate
  • CBNumber:CB8126078
  • Molecular Formula:C11H23N5O6
  • Formula Weight:321.33
  • MOL File:4320-30-3.mol
L-Arginine L-glutamate Property
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

L-Arginine L-glutamate Chemical Properties,Usage,Production

  • Originator Modamate,Abbott,US,1960
  • Uses L-Arginine L-Glutamate is used in the making of solution of arginine glutamate for the healing of radiation-induced skin ulcers in guinea pigs
  • Uses Intravenous ammonia detoxicant in cases of liver failure.
  • Definition ChEBI: Arginine glutamate is a glutamic acid derivative.
  • Manufacturing Process This salt may be prepared by mixing L-arginine with L-glutamic acid in water and crystallizing the resulting salt from the water by the addition of a polar water miscible organic solvent to the water. For instance, when 17.2 g of Larginine and 14.5 g of L-glutamic acid were dissolved in 155 g of water, a clear homogeneous solution resulted which had a pH of 5.3. This solution was filtered and the filtrate was evaporated at 50°C under reduced pressure to a solution having a solids content of about 45%. Absolute methanol (220 g) was added to the concentrated solution of the salt and this mixture cooled to 5°C for one hour. The resulting solid salt was removed from the mixture by filtration and washed with absolute methanol. After being dried preliminarily in the air, the salt was further dried in a vacuum oven at 60°C for 3 hours. The resulting salt, L-arginine-L-glutamate, weighed 30 g (94.6% of the theoretically possible yield based on the amount of L-arginine and L-glutamic acid employed) and melted at 193-194.5°C with decomposition.
  • brand name Modumate (Abbott).
  • Therapeutic Function Ammonia detoxicant (hepatic failure)
  • General Description White powder.
  • Air & Water Reactions Slightly soluble in water.
  • Reactivity Profile A dipeptide; hence an amide.
  • Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition L-Arginine L-glutamate emits toxic fumes.
L-Arginine L-glutamate Preparation Products And Raw materials
Raw materials
Preparation Products
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L-Arginine L-glutamate Spectrum
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  • C11H23N5O6C11H23N5O6
  • C6H14N4O2C5H9NO4
  • C11H23N5O6
  • 26242-32-2
  • 化合物 ARGININE GLUTAMATE
  • MODUMATE|||NSC-122009|||NSC 122009|||NSC122009|||NCI-C02120|||ARGIMATE
  • L-精氨酸 L-谷氨酸酯
  • 精谷氨酸
  • L-精氨酸-L-谷氨酸(CAS号:4320-30-3)
  • L-精氨酸-L-谷氨酸盐
  • L-精氨酸-L-谷氨酸
  • 精氨酸谷氨酸盐
  • 精氨酸谷氨酸
  • L-精氨酸 L-谷氨酸
  • L-谷氨酸L-精氨酸盐
  • L-精氨酸-L-谷氨盐
  • L-精氨酸 L-谷氨酰胺
  • L-精氨酸谷氨酸盐
  • L-精氨酸 L-谷氨酸 L-精氨酸-L-谷氨酸 L-精氨酸-L-谷氨酸盐 精氨酸谷氨酸 精氨酸谷氨酸盐
  • 4320-30-3
  • Puromycine
  • L-arginine glutamate USP/EP/BP
  • L-Arginine L-glutamate USP/EP/BP
  • (S)-2-aminopentanedioic acid (S)-2-amino-5-guanidinopentanoic acid
  • L-Glutamic acid, compd. with L-arginine (1:1)OTHER CA INDEX NAMES:L-Arginine, L-glutamate (1:1)
  • JACS-4320-30-3
  • L-Argenine-L-Glutamic
  • L-ARGININE L-GLUTAMATE COMPOUND
  • L-Arginie L-Glutamate
  • L-ARGININE1-GLUTAMATE
  • s(+)-2-amino-5-guanidinopentanoic acid l-glutamate salt