ChemicalBook > CAS DataBase List > 4-(Aminomethyl)benzoic acid

4-(Aminomethyl)benzoic acid

Description References

CAS No.56-91-7
Chemical Name:4-(Aminomethyl)benzoic acid
CBNumber:CB7742381
Molecular Formula:C8H9NO2
Formula Weight:151.16
MOL File:56-91-7.mol

4-(Aminomethyl)benzoic acid Property

Melting point ≥300 °C (lit.)
Boiling point 273.17°C (rough estimate)
Density 1.2023 (rough estimate)
refractive index 1.5810 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated)
form Powder
pka 3.75±0.10(Predicted)
color White to almost white
Water Solubility Slightly soluble in water. Insoluble in ethanol, benzene and chloroform.
BRN 1100606
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey QCTBMLYLENLHLA-UHFFFAOYSA-N
CAS DataBase Reference 56-91-7(CAS DataBase Reference)
FDA UNII 68WG9JKC7L
ATC code B02AA03
UNSPSC Code 41116107
NACRES NA.24

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36-37/39-26,37/39
WGK Germany :3
HS Code :29224999

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338

4-(Aminomethyl)benzoic acid Price More Price(12)

Brand: Sigma-Aldrich(India)
Product number: 283746
Product name : 4-(Aminomethyl)benzoic acid
Purity: 97%
Packaging: 5G
Price: ₹1850
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 283746
Product name : 4-(Aminomethyl)benzoic acid
Purity: 97%
Packaging: 25G
Price: ₹6190
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 283746
Product name : 4-(Aminomethyl)benzoic acid
Purity: 97%
Packaging: 100G
Price: ₹15523.05
Updated: 2022/06/14
Buy: Buy

Brand: ALFA India
Product number: ALF-B23519-36
Product name : 4-(Aminomethyl)benzoic acid, 97%
Purity:
Packaging: 500g
Price: ₹21288
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: A0965
Product name : 4-(Aminomethyl)benzoic Acid
Purity:
Packaging: 25G
Price: ₹4800
Updated: 2022/05/26
Buy: Buy

4-(Aminomethyl)benzoic acid Chemical Properties,Usage,Production

Description 4-(Aminomethyl)benzoic acid is a organic compound that can serve as a type 2 antifibrinolytic agent used in the treatment of fibrotic skin disorders, such as Peyronie's disease. It is believed that 4-(Aminomethyl)benzoic acid is effective to increase the oxygen uptake at the tissue level and enhance activity of monoamine oxidase, thus to promote the degradation of serotonin, which in excess, may lead to fibrotic changes. It is also administrated by mouth to treat several skin conditions including vitiligo, pemphigus, dermatomyositis, morphea, lymphoblastoma cutis and scleroderma. It is sometimes used in pill form by patients suffering from irritable bowel syndrome to treat the relevant gastrointestinal symptoms and applied in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels. Besides, it can also serve as nutritional supplements to darken gray hair, prevent hair loss, make skin look younger and prevent sunburn and its benefits are claimed for people with fatigue, irritability, depression, weeping eczema, scleroderma, patchy pigment loss in skin, and premature grey hair.
References https://en.wikipedia.org/wiki/4-Aminobenzoic_acid
https://www.alfa.com/en/catalog/B23519/
https://pubchem.ncbi.nlm.nih.gov/compound/4-aminobenzoic_acid#section=Top
http://www.webmd.com/vitamins-supplements/ingredientmono-1004-PABA+PARA-AMINOBENZOIC+ACID+PABA.aspxactiveIngredientId=1004&activeIngredientName=PABA
Chemical Properties white to light yellow crystal powde
Uses 4-(Aminomethyl)benzoic acid (PAMBA) can be used in the synthesis of:
- Cobalt carboxy phosphonates.
- Apoptozole (Az), which has cellular potency to promote membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel activity.
- Cyclopeptide composed of L-glutamic acid and 3-aminobenzoic acid that can be used as receptors for a variety of cations and anions.
- A bioactive peptide which has potent GPR54 (a G protein-coupled receptor) agonistic activity.
Uses 4-(Aminomethyl)benzoic Acid is a type 2 antifibrinolytic agent.
Uses 4-(Aminomethyl)benzoic acid acts as an unnatural amino acid derivative. It is also used as a type 2 antifibrinolytic agent. Further, it reacts with 2-methyl-isothiourea sulfate to prepare 4-guanidinomethylbenzoic acid.
Definition ChEBI: Aminomethylbenzoic acid is a member of benzoic acids.
reaction suitability reaction type: solution phase peptide synthesis