ChemicalBook > CAS DataBase List > 2,2,2-Trichloro-1-phenylethanol
2,2,2-Trichloro-1-phenylethanol
2,2,2-Trichloro-1-phenylethanol
- CAS No.2000-43-3
- Chemical Name:2,2,2-Trichloro-1-phenylethanol
- CBNumber:CB7351129
- Molecular Formula:C8H7Cl3O
- Formula Weight:225.5
- MOL File:2000-43-3.mol
2,2,2-Trichloro-1-phenylethanol Property
- Melting point 37 °C
- Boiling point 93-96°C 0,8mm
- Density 1.4250 (rough estimate)
- refractive index 1.5690
- Flash point 93-96°C/0.8mm
- storage temp. 2-8°C
- pka 11.92±0.20(Predicted)
- Water Solubility Not miscible in water.
- BRN 510385
- CAS DataBase Reference 2000-43-3(CAS DataBase Reference)
- EPA Substance Registry System Benzenemethanol, .alpha.-(trichloromethyl)- (2000-43-3)
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H303-H315-H319
- Precautionary statements P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313
2,2,2-Trichloro-1-phenylethanol Chemical Properties,Usage,Production
- Physical properties Colorless, slightly viscous liquid. Almost insoluble in water, soluble in alcohol and oils. Very faint, metallic-green, musty-floral odor of good tenacity.
- Uses 2,2,2-Trichloro-1-phenylethanol is used as pharmaceutical intermediate.
- Production Methods 2,2,2-Trichloro-1-phenylethanol can be produced 1) from Chloral with Aluminum trichloride in Benzene. 2) from Benzaldehyde and Chloroform.
-
Synthesis Reference(s)
Canadian Journal of Chemistry, 58, p. 485, 1980
Tetrahedron Letters, 19, p. 1521, 1978 DOI: 10.1016/S0040-4039(01)94592-7 - Safety Profile Moderately toxic by subcutaneousroute. When heated to decomposition it emits toxicvapors of Clí.
2,2,2-Trichloro-1-phenylethanol Preparation Products And Raw materials
Raw materials
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