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Propargyl-PEG3-Bromide

Propargyl-PEG3-Bromide Structure
Propargyl-PEG3-Bromide
  • CAS No.203740-63-0
  • Chemical Name:Propargyl-PEG3-Bromide
  • CBNumber:CB73062622
  • Molecular Formula:C9H15BrO3
  • Formula Weight:251.12
  • MOL File:203740-63-0.mol
Propargyl-PEG3-Bromide Property
  • Boiling point 287.8±25.0 °C(Predicted)
  • Density 1.300±0.06 g/cm3(Predicted)
  • solubility Soluble in DMSO, DCM, DMF
  • form Liquid
  • color Colorless to light yellow
Safety
  • HS Code  :2942000090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Propargyl-PEG3-Bromide Chemical Properties,Usage,Production

  • Description Propargyl-PEG3-bromide comprises a propargyl group and a bromide group. The propargyl group reacts with azide-bearing compounds or biomolecules in Click Chemistry to yield a stable triazole linkage; copper will be needed as a catalyst.
  • Uses Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG3-Bromide Preparation Products And Raw materials
Raw materials
Preparation Products
Global(50)Suppliers
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  • Supplier: Borenpharm Co., Ltd
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Propargyl-PEG3-Bromide Spectrum
203740-63-0, Propargyl-PEG3-BromideRelated Search:
  • peg
  • PEG系列产品-Propargy-PEG系列
  • 助剂
  • 丙炔-PEG3-溴
  • 炔丙基-三聚乙二醇-溴
  • BR-PEG3-PROPARGYL
  • 3-(2-(2-(2-溴乙氧基)乙氧基)乙氧基)丙-1-炔
  • 炔丙基PEG3-溴化物
  • 丙炔基-PEG3-溴
  • 丙炔基-三聚乙二醇-溴代
  • 丙炔-三聚乙二醇-溴
  • 炔-三聚乙二醇-溴
  • 203740-63-0
  • 3- (2- (2- (2-bromoethoxy) ethoxy) ethoxy) propa-1-yne
  • Propargyl-PEG3-Br/1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
  • 3-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)prop-1-yne
  • 1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
  • PROPARGYL-PEG3-BR
  • Alkyne-PEG3-Br
  • Propargyl-PEG3-Bromide