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Benzyl-PEG5-Azide

Benzyl-PEG5-Azide Structure
Benzyl-PEG5-Azide
  • CAS No.86770-72-1
  • Chemical Name:Benzyl-PEG5-Azide
  • CBNumber:CB73048688
  • Molecular Formula:C17H27N3O5
  • Formula Weight:353.41338
  • MOL File:86770-72-1.mol
Benzyl-PEG5-Azide Property
  • solubility Soluble in Water, DMSO, DCM, DMF
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Benzyl-PEG5-Azide Chemical Properties,Usage,Production

  • Description Bromoacetamido-PEG2-azide is a heterobifunctional PEG linker containing a reactive bromoacetamido and a terminal azide.The bromoacetamidogroup is a very reactive group for nucleophilic substitution. The azide group can react with alkyne, BCN, DBCO via Click Chemistry.
  • Uses Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Benzyl-PEG5-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Benzyl-PEG5-Azide Suppliers
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  • Supplier： Borenpharm Co., Ltd
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Benzyl-PEG5-Azide Spectrum
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