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Bromo-PEG2-CH2CO2tBu

Bromo-PEG2-CH2CO2tBu Structure
Bromo-PEG2-CH2CO2tBu
  • CAS No.1807518-63-3
  • Chemical Name:Bromo-PEG2-CH2CO2tBu
  • CBNumber:CB73062440
  • Molecular Formula:C10H19BrO4
  • Formula Weight:283.16
  • MOL File:1807518-63-3.mol
Bromo-PEG2-CH2CO2tBu Property
  • Boiling point 316.4±22.0 °C(Predicted)
  • Density 1.269±0.06 g/cm3(Predicted)
  • form liquid
  • color Clear
Safety
  • HS Code  :2942000090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P271-P261-P280

Bromo-PEG2-CH2CO2tBu Chemical Properties,Usage,Production

  • Description Bromo-PEG2-CH2CO2tBu is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
  • Uses Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs; Alkyl/ether
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG2-CH2CO2tBu Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG2-CH2CO2tBu Suppliers
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Bromo-PEG2-CH2CO2tBu Spectrum
1807518-63-3, Bromo-PEG2-CH2CO2tBuRelated Search:
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  • 1807518-63-3
  • Acetic acid, 2-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester
  • Br-PEG2-CH2-Boc
  • Br-PEG2-CH2COOtBu/Acetic acid, 2-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester
  • Bromo-PEG-2-CH2-Boc,BromoPEG2CH2Boc,inhibit,Bromo PEG2 CH2 Boc,PROTAC Linkers,Inhibitor
  • t-butyl acetate-PEG2-bromide BROMO-PEG2-CH2CO2TBU
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  • tert-Butyl 2-[2-(2-bromoethoxy)ethoxy]acetate
  • CAS_1807518-63-3
  • t-butyl acetate-PEG2-bromide
  • Br-PEG2-CH2COOtBu
  • t-butyl acetate-PEG2-bromiade
  • Bromo-PEG2-CH2COOtBu
  • Bromo-PEG2-CH2CO2tBu

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