ChemicalBook > CAS DataBase List > Tolperisone hydrochloride
Tolperisone hydrochloride
Tolperisone hydrochloride
- CAS No.3644-61-9
- Chemical Name:Tolperisone hydrochloride
- CBNumber:CB7200340
- Molecular Formula:C16H24ClNO
- Formula Weight:281.82
- MOL File:3644-61-9.mol
Tolperisone hydrochloride Property
- Melting point 181-183°C
- storage temp. room temp
- solubility H2O: >20mg/mL
- form solid
- color white
- PH pH(50g/l, 25℃) : 4.5~5.5
- Water Solubility almost transparency
- Merck 14,9522
- CAS DataBase Reference 3644-61-9(CAS DataBase Reference)
- FDA UNII 8Z075K2TIG
- UNSPSC Code 12352200
- NACRES NA.77
Safety
- Hazard Codes :Xn,Xi
- Risk Statements :20/21/22-52/53-36/37/38
- Safety Statements :26-36-45-61-36/37-37/39
- WGK Germany :3
- RTECS :UH1575500
- Toxicity :LD50 s.c. in mice: 620 mg/kg (Porszasz, 1961)
-
NFPA 704:
0 3 0
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302+H312+H332
- Precautionary statements P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Tolperisone hydrochloride Price
More Price(2)
- Brand: Sigma-Aldrich(India)
- Product number: T3577
- Product name : Tolperisone hydrochloride
- Purity: ≥98% (HPLC), solid
- Packaging: 50MG
- Price: ₹12308.03
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: T3577
- Product name : Tolperisone hydrochloride
- Purity: ≥98% (HPLC), solid
- Packaging: 250MG
- Price: ₹49199.63
- Updated: 2022/06/14
- Buy: Buy
Tolperisone hydrochloride Chemical Properties,Usage,Production
- Chemical Properties White Solid
- Originator Tolperisone hydrochloride,Shanghai Abochem Chemical Co.
- Uses Tolperisone hydrochloride can be used as a muscle relaxant.
- Definition ChEBI: Tolperisone hydrochloride is an aromatic ketone.
- Manufacturing Process To 1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanol in chloroform was added an excess of thionyl chloride and the reaction mixture refluxed until completed. It was then taken to dryness under reduced pressure and the residue crystallized by dissolving in hot alcohol and diluting with ethyl acetate. An aqueous solution of the obtained N-[3-chloro-3-(p-tolyl)propyl]piperidine hydrochloride was hydrogenated at 3 atmospheres in the presence of buffered palladium-on-charcoal catalyst. 1-Piperidino-2-methyl-3-(p-tolyl)-3-propanone was purified by distilling the base (boiling point 106-107°C/1 mm) and reconverting to the hydrochloride, melting point 216-217°C.
- Therapeutic Function Muscle relaxant, Vasodilator
- Biochem/physiol Actions Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.
Tolperisone hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global(318)Suppliers
-
Supplier:
- Tel: +8615531157085
- Email:abby@chuanghaibio.com
- Country:China
- ProdList:8808
- Advantage:58
-
Supplier:
- Tel:+86 13288715578<br/>+8613288715578
- Email:sales@hbmojin.com
- Country:China
- ProdList:12810
- Advantage:58
-
Supplier:
- Tel:+86-18353166132<br/>+86-18353166132
- Email:sales02@airuikechemical.com
- Country:China
- ProdList:983
- Advantage:58
-
Supplier:
- Tel:+86-18600796368<br/>+86-18600796368
- Email:sales@sjar-tech.com
- Country:China
- ProdList:485
- Advantage:58
-
Supplier:
- Tel:+86-(0)57185586718<br/>+86-13336195806
- Email:sales@capot.com
- Country:China
- ProdList:29730
- Advantage:60
-
Supplier:
- Tel:+86-0371-55170693<br/>+86-19937530512
- Email:info@tianfuchem.com
- Country:China
- ProdList:21628
- Advantage:55
-
Supplier:
- Tel:+86-21-33585366 - 03@
- Email:sales03@shyrchem.com
- Country:CHINA
- ProdList:738
- Advantage:60
-
Supplier:
- Tel:+8615102730682
- Email:bruce@xrdchem.cn
- Country:CHINA
- ProdList:566
- Advantage:55
-
Supplier:
- Tel:+86-0371-86658258<br/>+8613203830695
- Email:sales@coreychem.com
- Country:China
- ProdList:29859
- Advantage:58
-
Supplier:
- Tel:18871490254
- Email:linda@hubeijusheng.com
- Country:CHINA
- ProdList:28172
- Advantage:58
3644-61-9, Tolperisone hydrochlorideRelated Search:
- M-METHYLPROPIOPHENONE Tolperisone Impurity A Tolperisone Impurity B Paroxetine hydrochloride Tolperisone Impurity C ETHYL-O-TOLYL KETONE 4'-Methylacetophenone 4'-Methylpropiophenone 1-(4-Ethylphenyl)-2-methyl-2-propen-1-one 1-(4-Ethylphenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride 2-methyl-1-phenyl-3-(1-piperidyl)propan-1-one 1-Propanone, 1-(2-ethylphenyl)-2-methyl-3-(1-piperidinyl)-, hydrochloride (1:1) Eperisone Impurity 6(Hydrochloride) 3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE Eperisone hydrochloride 3-(diethylamino)propiophenone Tolperisone hydrochloride Tolperisone
- Pharmaceuticals
- Intermediates & Fine Chemicals
- 抑制剂
- 杂质对照品
- 对照品-杂质对照品
- 药靶配体
- 助剂
- 原料药
- 日用化学品
- 医药原材料
- 化学试剂
- 医药原料药
- 科研试剂
- 原料
- 医药原料
- 其他化学试剂
- 小分子抑制剂
- C16H24NOCl
- C16H23NOHClC16H24ClNO
- C16H23NOHCl
- 3644-61-8
- 3944-61-9
- 盐酸托哌酮,10 MM DMSO 溶液
- 2-甲基-3-(哌啶-1-基)-1-(对甲苯基)丙-1-酮盐酸盐
- 盐酸乙哌立松杂质P
- 乙哌立松杂质2 盐酸盐
- 盐酸托哌酮|||MUSCALM|||MIDOCALM|||托哌酮盐酸盐|||TOLPERISONE HCL
- 盐酸托派酮
- 盐酸托培松
- 盐酸托哌酮/甲苯哌丙酮
- TOLPERISONE HYDROCHLORIDE 盐酸甲苯哌丙酮
- 甲苯哌丙酮(盐酸甲苯哌丙酮)
- 托哌酮杂质
- 盐酸托利酮
- 盐酸托哌酮(脑脉宁)
- 甲苯哌丙酮/盐酸托哌酮
- TOLPERISONE 盐酸盐
- 2-METHYL-1-(4-METHYLPHENYL)-3-(1-PIPERIDYL)PROPAN-1-ONE 盐酸盐
- 盐酸托哌酮价格
- 盐酸脑脉宁
- 盐酸甲苯哌丙酮
- 托哌酮盐酸盐
- 甲苯哌丙酮
- 盐酸甲哌酮
- 甲苯哌丙酮 盐酸盐
- 脑脉宁
- 盐酸托哌酮
- 4'-甲基-2-(1-哌啶基甲基)苯丙酮盐酸盐
- 3644-61-9
- Tolperisone hydrochloride, 10 mM in DMSO
- Impurity P of Epirisone Hydrochloride
- Eperisone Impurity 18
- Eperisone Impurity 2 HCl
- 2-Methyl-3-(piperidin-1-yl)-1-(p-tolyl)propan-1-one hydrochloride
- Muscalm|||Midocalm|||Tolperisone HCl
- Tolperisone HCl Reference Standard
- Toperidone hydrochloride
- TIANFU CHEM Tolperisone hydrochloride