Ginsenoside Ra2

Uses

Ginsenoside Ra2 is a natural product, a ginsenoside from stems and leaves of Panax ginseng. A new dammarane-saponin. A Panax ginseng and an immune regulator.

Synthesis

Ginseng 5 kg, add water decoction extraction three times, each time the amount of water were 12, 10, 8 times the weight of ginseng, decoction time were 2, 1.5, 1 hours, combined decoction, over D4020 large pore adsorbent resin adsorption, rinsed with water, 85% ethanol elution to the eluent can not be detected in the ginsenoside Rg1 and ginsenoside Rb1 (silica gel thin-layer chromatography, n-butanol: ethyl acetate: water = 4:1:5, the upper layer, 10% sulfuric acid spray, 105 heating color, the same below) so far, the eluent recovered ethanol, obtained 351 grams of total ginsenosides, the total ginsenosides. Water = 4:1:5, the upper layer, 10% sulfuric acid spray, 105 heating color, the same below) until the eluent recovery of ethanol, ginsenoside 351 grams of total saponin. . Ginsenoside 10 grams, dissolved in water on the alumina column, first eluted with water to the eluent can not be detected ginsenoside Re, ginsenoside Rg1 until the eluent over the AB-8 large pore adsorbent resin adsorption, ethanol elution, decompression recovery of solvents, ginseng saponin 3.1 grams of the three alcohol group, the TLC examination, which the main components are ginsenoside Re, ginsenoside Rg1. then with 50% tetrahydrofuran ground water, the main component is the ginsenoside Re, ginsenoside Rg1. The main components were ginsenoside Re and ginsenoside Rg1. Then it was eluted with 50% tetrahydrofuran aqueous solution until ginsenoside Rb1 was not detected in the eluate. The eluent was decompressed to recover the solvent, and 5.2 g of ginsenosides were obtained from the diol group. After TLC examination, the main components are ginsenoside Ra1, ginsenoside RA2, ginsenoside Ra3, ginsenoside Rb1, ginsenoside Rb2, ginsenoside Rb3, ginsenoside Rc, ginsenoside Rd, and other diol ginsenosides.