ChemicalBook > CAS DataBase List > Ginsenoside Rk3
Ginsenoside Rk3
Ginsenoside Rk3
- CAS No.364779-15-7
- Chemical Name:Ginsenoside Rk3
- CBNumber:CB12604175
- Molecular Formula:C36H60O8
- Formula Weight:620.87
- MOL File:364779-15-7.mol
Ginsenoside Rk3 Property
- Boiling point 722.4±60.0 °C(Predicted)
- Density 1.20±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp. 4°C, protect from light
- solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form Powder
- pka 12.91±0.70(Predicted)
- color White to off-white
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Ginsenoside Rk3 Chemical Properties,Usage,Production
- Uses Ginsenoside Rk3 is isolated from the root of Panax notoginseng which exhibits high inhibitory activity against Epidermophyton floccosum, Trichophyton rubrum, and Trichophyton mentagrophytes.
-
in vivo
The inhibitory effects of Ginsenoside Rk3 (Rk3) on tumor progression are studied in vivo using a H460 xenograft model in nude mice. Compared with the control group, a significant inhibition of tumor growth (volume) is observed in the Ginsenoside Rk3-treated group. Twenty-one days after treatment initiation, tumor growth is significantly inhibited by approximately 62.99% in the mice receiving 20 mg/kg Ginsenoside Rk3, similar to the inhibitory effect observed in the 20 mg/kg Gefitinib-treated group (57.21%). Compared with the control group, tumor growth is moderately inhibited in the mice receiving 10 and 5 mg/kg Ginsenoside Rk3, with inhibition rates of 32.54% and 11.84%, respectively[2].
- IC 50 NF-κB: 14.24 μM (IC50, in HepG2 cells); NF-κB: 15.32 μM (IC50, in SK-Hep1 cell)
Ginsenoside Rk3 Preparation Products And Raw materials
Raw materials
Preparation Products
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- Ginsenoside Rk3, 10 mM in DMSO
- β-D-Glucopyranoside, (3β,6α,12β)-3,12-dihydroxydammara-20,24-dien-6-yl
- Ginsenoside Rk3 standard
- Ginsenoside Rk3