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Ethyl 2-(ethoxymethylene)acetoacetate

Ethyl 2-(ethoxymethylene)acetoacetate Structure
Ethyl 2-(ethoxymethylene)acetoacetate
  • CAS No.3788-94-1
  • Chemical Name:Ethyl 2-(ethoxymethylene)acetoacetate
  • CBNumber:CB6475655
  • Molecular Formula:C9H14O4
  • Formula Weight:186.21
  • MOL File:3788-94-1.mol
Ethyl 2-(ethoxymethylene)acetoacetate Property
  • Boiling point 266°C(lit.)
  • Density 1.049±0.06 g/cm3(Predicted)
  • refractive index 1.4730 to 1.4770
  • storage temp. Keep in dark place,Sealed in dry,Room Temperature
  • form powder to lump to clear liquid
  • color Light yellow to Yellow to Orange
  • CAS DataBase Reference 3788-94-1(CAS DataBase Reference)
Safety
  • HS Code  :2916399090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301+H311+H331-H314-H335-H412-H226
  • Precautionary statements P501-P261-P273-P270-P240-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P361+P364-P303+P361+P353-P301+P330+P331-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P403+P235-P405
Ethyl 2-(ethoxymethylene)acetoacetate Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: E1148
  • Product name : Ethyl 2-Acetyl-3-ethoxyacrylate
  • Purity: min. 98.0 %(total of isomer)
  • Packaging: 5G
  • Price: ₹8000
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: E1148
  • Product name : Ethyl 2-Acetyl-3-ethoxyacrylate
  • Purity: min. 98.0 %(total of isomer)
  • Packaging: 25G
  • Price: ₹16500
  • Updated: 2022/05/26
  • Buy: Buy

Ethyl 2-(ethoxymethylene)acetoacetate Chemical Properties,Usage,Production

  • Uses Ethyl 2-(ethoxymethylene)acetoacetate is an active metabolite of leflunomide, a pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties that reduces the number of activated central nervous system lymphocytes.
  • Application Ethyl 2-(ethoxymethylene)acetoacetate is a mono-, di-, and trifunctional three-carbon electrophile in carbonyl reactions and cyclization reactions; a β-ketoester equivalent.
  • Preparation Ethyl 2-(ethoxymethylene)acetoacetate is obtained by heating Ethyl Acetoacetate with Triethyl Orthoformate in Acetic  Anhydride.
  • storage May be kept for a few weeks at 0 °C in the dark with addition of  hydroquinone. The enol ether hydrolyses slowly in contact with water. Use in a fume hood.
Ethyl 2-(ethoxymethylene)acetoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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Ethyl 2-(ethoxymethylene)acetoacetate Spectrum
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  • Ethyl (2E)-2-(ethoxymethylene)-3-oxobutanoate
  • (E)-ethyl 2-(ethoxymethylene)-3-oxobutanoate
  • 2-(ethoxymethylene)-3-oxo-Butanoic acid ethyl ester (9CI ACI)
  • Butanoic acid, 2-(ethoxymethylene)-3-oxo-, ethyl ester (9CI, ACI)
  • Ethyl (E)-2-(ethoxymethylene)-3-oxobutanoate
  • (Z)-ethyl 2-(ethoxyMethylene)-3-oxobutanoate
  • Teriflunomide Impurity 9 (Ethyl 2-(Ethoxymethylene)acetoacetate)
  • Ethyl 2-(ethoxymethylidene)-3-oxobutanoate
  • Butanoic acid, 2-(ethoxymethylene)-3-oxo-, ethyl ester
  • ene)-3-oxobutanoate
  • 2-(ethoxymethyL
  • Ethyl2-Acetyl-3-ethoxyacrylate&gt
  • 2-(ETHOXYMETHYLENE)-3-OXO-BUTANOIC
  • 2-(Ethoxymethylene)acetoacetic acid ethyl ester
  • Ethyl 2-(ethoxymethylene)acetoacetate/ 2-(Ethoxymethylene)-3-oxo-butanoic acid ethyl ester/ ethyl 2-(ethoxymethylene)-3-oxobutanoate
  • Ethyl 2-acetyl-3-ethoxyacrylate
  • ethyl (2Z)-2-(ethoxyMethylidene)-3-oxobutanoate
  • 2-ETHOXYMETHYLENE-3-OXO-BUTYRIC ACID ETHYL ESTER
  • Acetoacetic acid, 2-(ethoxyMethylene)-, ethyl ester
  • Einecs 223-259-3
  • 2-Acetyl-3-ethoxyacrylic acid ethyl ester
  • 2-(ETHOXYMETHYLENE)-3-OXO-BUTANOIC ACID,ETHYL ESTER 98+%
  • ETHYL A-(ETHOXYMETHYLENE)ACETOACETATE
  • Ethyl-(ethoxymethylene)acetoacetate
  • ethyl 2-(ethoxymethylene)acetoacetate
  • 2-(ETHOXYMETHYLENE)-3-OXO-BUTANOIC ACID,ETHYL ESTER