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4-Pyrazoleboronic acid pinacol ester

4-Pyrazoleboronic acid pinacol ester Structure
4-Pyrazoleboronic acid pinacol ester
  • CAS No.269410-08-4
  • Chemical Name:4-Pyrazoleboronic acid pinacol ester
  • CBNumber:CB6449821
  • Molecular Formula:C9H15BN2O2
  • Formula Weight:194.04
  • MOL File:269410-08-4.mol
4-Pyrazoleboronic acid pinacol ester Property
  • Melting point 142-146 °C (lit.)
  • Boiling point 335.4±15.0 °C(Predicted)
  • Density 1.09±0.1 g/cm3(Predicted)
  • storage temp. Keep in dark place,Sealed in dry,Room Temperature
  • solubility DMSO, Ethyl Acetate, Methanol
  • form Powder
  • pka 13.36±0.50(Predicted)
  • color Off-white to tan
  • Water Solubility insoluble
  • InChIKey TVOJIBGZFYMWDT-UHFFFAOYSA-N
  • CAS DataBase Reference 269410-08-4(CAS DataBase Reference)
  • UNSPSC Code 12352103
  • NACRES NA.22
Safety
  • Hazard Codes  :Xi,F
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36
  • WGK Germany  :3
  • Hazard Note  :Irritant/Flammable
  • TSCA  :No
  • HS Code  :29331990
  • NFPA 704:
    1
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338
4-Pyrazoleboronic acid pinacol ester Price More Price(7)
  • Brand: Sigma-Aldrich(India)
  • Product number: 525057
  • Product name : 4-Pyrazoleboronic acid pinacol ester
  • Purity: 97%
  • Packaging: 1G
  • Price: ₹5693.95
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 525057
  • Product name : 4-Pyrazoleboronic acid pinacol ester
  • Purity: 97%
  • Packaging: 5G
  • Price: ₹24356.25
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 525057
  • Product name : 4-Pyrazoleboronic acid pinacol ester
  • Purity: 97%
  • Packaging: 25G
  • Price: ₹79823.55
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-L19654-06
  • Product name : 1H-Pyrazole-4-boronic acid pinacol ester, 98%
  • Purity: 
  • Packaging: 5g
  • Price: ₹9325
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-L19654-03
  • Product name : 1H-Pyrazole-4-boronic acid pinacol ester, 98%
  • Purity: 
  • Packaging: 1g
  • Price: ₹2153
  • Updated: 2022/05/26
  • Buy: Buy

4-Pyrazoleboronic acid pinacol ester Chemical Properties,Usage,Production

  • Chemical Properties Off-white to tan powder
  • Uses Reagent used for
    • Suzuki-Miyaura cross-couplings
    • Ruthenium-catalyzed asymmetric hydrogenation

    Reagent used in preparation of inhibitors of many highly significant therapeutic enzymes and kinases containing the privileged scaffold pyrazole, including
    • VEGF
    • Aurora
    • Rho (ROCK)
    • Janus Kinase 2 (JAK)
    • c-MET
    • ALK
    • S-nitrosoglutathione reductase
    • CDC7
    • Acetyl-CoA carboxylase
    • Prosurvival Bcl-2 protein
    • Viral RNA-Dependent RNA polymerase
    • Long Chain Fatty Acid Elongase 6
    • PI3
    • AKT
    • Chk1
    • Protein Kinase B
  • Uses 1H-Pyrazole-4-boronic acid pinacol ester is a useful reagent for Suzuki-Miyaura cross-couplings as well as Ruthenium-catalyzed asymmetric hydrogenation. It is also used as reagent for preparing VEGF, Aurora, RHO (ROCK), Janus Kinase 2, c-MET, ALK, S-nitrsoflutathione reductase, CDC7, Acetyl-CoA carboxylase inhibitors as well as other biologically active compounds.
  • Uses 4-Pyrazoleboronic Acid Pinacol Ester is used in the preparation of Rho kinase (ROCK) inhibitors as wella s other biologically active compounds.
4-Pyrazoleboronic acid pinacol ester Preparation Products And Raw materials
Raw materials
Preparation Products
4-Pyrazoleboronic acid pinacol ester Suppliers
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4-Pyrazoleboronic acid pinacol ester Spectrum
269410-08-4, 4-Pyrazoleboronic acid pinacol esterRelated Search:
  • 269410-08-4
  • OLED materials,pharm chemical,electronic
  • Boronic acid
  • API intermediates
  • Pyrazole series
  • organic or inorganic borate
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  • Boronate Esters
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  • Organometallic Reagents
  • Heteroaryl
  • C9H15BN2O2
  • CH34C2O2BC3N2H3
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