ChemicalBook > CAS DataBase List > 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID

3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID

3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Structure
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
  • CAS No.67-30-1
  • Chemical Name:3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
  • CBNumber:CB6124010
  • Molecular Formula:C14H8I4O4
  • Formula Weight:747.83
  • MOL File:67-30-1.mol
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Property
  • Melting point 219-220 °C (decomp)
  • Boiling point 544.8±50.0 °C(Predicted)
  • Density 2.727±0.06 g/cm3(Predicted)
  • storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
  • solubility acetone: soluble19.60 - 20.40mg/mL, clear, colorless (or faintly yellow to yellow)
  • form powder to crystal
  • pka 3.98±0.10(Predicted)
  • color White to Yellow to Green
  • InChIKey PPJYSSNKSXAVDB-UHFFFAOYSA-N
  • FDA UNII PA7UX1FFYQ
  • UNSPSC Code 12352106
  • NACRES NA.77
Safety
  • Hazard Codes  :T+
  • Risk Statements  :28
  • Safety Statements  :45
  • RIDADR  :UN 2811 6.1/PG 1
  • WGK Germany  :3
  • RTECS  :CY1585800
  • HS Code  :2916.39.7900
  • NFPA 704:
    0
    4 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300
  • Precautionary statements P264-P301+P310
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: T3787
  • Product name : 3,3′,5,5′-Tetraiodothyroacetic acid
  • Purity: 
  • Packaging: 25MG
  • Price: ₹12676.08
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: T3787
  • Product name : 3,3′,5,5′-Tetraiodothyroacetic acid
  • Purity: 
  • Packaging: 100MG
  • Price: ₹36534.38
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: T3730
  • Product name : 3,3',5,5'-Tetraiodothyroacetic Acid
  • Purity: 
  • Packaging: 100MG
  • Price: ₹6200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: T3730
  • Product name : 3,3',5,5'-Tetraiodothyroacetic Acid
  • Purity: 
  • Packaging: 500MG
  • Price: ₹16800
  • Updated: 2022/05/26
  • Buy: Buy

3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Chemical Properties,Usage,Production

  • Uses Thyroid hormone analogue
  • Uses 3,3′,5,5′-Tetraiodothyroacetic acid has been used:
    • as a positive control to study the effects of ioxynil (IOX)
    • diethylstilbestrol (DES) exposure on zebrafish embryos
    • to study its effects on long-term potentiation (LTP) and long-term depression (LTD) in the dentate gyrus in urethane-anesthetized male rats
    • to determine its influence on the actions of thyroid-stimulating hormone
    • thyroid-stimulating immunoglobulins in orbital fibroblast

  • Definition ChEBI: A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'.
  • Biochem/physiol Actions Studies in rats have reported that Tetrac may regulate TSH secretion under in vivo conditions1.
  • in vivo

    Tetrac (35 μg; p.o. for 40 days) inhibits tumor inoculation, growth and integrin expression in mice[4].

    Animal Model:Wild-type male Balb/C mice aged 8 weeks are inoculated with 102B16F10 or B16LS9 cells[4]
    Dosage:35 μg per day
    Administration:P.o. (added to the drinking water) daily for 40 days
    Result:Delayed the onset of ocular melanoma.
    Reduced the S-100 and integrin staining level in the B16F10 mice model.
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Spectrum
67-30-1, 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACIDRelated Search:
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Impurities
  • Drug Analogues
  • Aromatics
  • Aromatic Phenylacetic Acids and Derivatives
  • 抑制剂
  • 配体家族
  • 杂质对照品
  • 有机中间体
  • 合成
  • C14H8O4I4
  • C14H8I4O4
  • 1246812-40-8
  • 1373321-04-1
  • 四碘甲状腺乙酸,10 MM DMSO 溶液
  • 四碘甲状腺乙酸(TA4)
  • 3,3'',5,5''-四碘甲腺-乙酸
  • L-甲状腺素杂质4(L-甲状腺素EP杂质D)
  • 碘甲状腺素EP杂质D
  • 化合物TAK875
  • 2-(4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基)乙酸
  • T4-乙酸
  • 3,3′,5,5′-四硫代甲酰乙酸
  • 左甲状腺素钠BP杂质D
  • 碘塞罗宁 EP杂质D
  • 碘塞罗宁杂质D (EP)
  • 左甲状腺素EP杂质D
  • 左甲状腺素–杂质D
  • 4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯乙酸
  • 四碘甲状腺乙酸
  • 3,3',5,5'-四碘甲腺-乙酸
  • 左旋甲状腺素EP杂质D
  • 67-30-1
  • Tetrac, 10 mM in DMSO
  • 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic Acid (Tetraiodothyroacetic Acid)
  • Levothyroxine EP Impurity-D (T4 acetic acid)
  • LEVOTHYROXINE EP IMPURITY D | T4-ACETIC ACID (USP)
  • Linagliptin Impurity CD10097
  • 3，5，3’，5’-Tetraiodo Thyroacetic Acid
  • Levothyroxine Sodium EP Impurity D
  • Liothyronine Sodium EP Impurity D
  • 3,5,3’,5’-tetraiodothyroacetique
  • Liothyronine EP Impurity D (Tetraiodothyroacetic Acid/ Levothyroxine EP Impurity D/ T4-Acetic Acid)
  • Levothyroxine EP Impurity D/ T4-Acetic Acid (Liothyronine EP Impurity D/ Tetraiodothyroacetic Acid)
  • Levothyroxine impurity 14/Liothyronine EP Impurity D/2-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid
  • Levothyroxine Impurity 4（Levothyroxine EP Impurity D）
  • Liothyronine EP Impurity D
  • Levothyroxine – Impurity D
  • (4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-aceticaci
  • TETRAC
  • Levothyroxine EP Impurity D
  • Benzeneacetic acid,4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-
  • 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetic acid, Tetrac
  • 3,5,3',5'-Tetraiodothyroacetic acid
  • 2-[3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)phenyl]acetic acid
  • [3,5-Diiodo-4-(3,5-diiodo-4-hydroxyphenoxy)phenyl]acetic acid
  • 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID

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