Chemical Properties
[α] 25 D +25.2° [5 % solution in 1 M HCl:95 % ethanol (1:2)], off-White Solid.
Uses
Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism.
Uses
3,5-Diiodo-L-thyronine is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.
Definition
ChEBI: (2S)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid is a phenylalanine derivative.
Flammability and Explosibility
Not classified
Pharmacology
3,5-Diiodo-L-thyronine is a thyroid hormone with a l-thyroxine-like activity.
Purification Methods
Recrystallise it from EtOH. [Chambers et al. J Chem Soc 3424 1949, Beilstein 14 II 226, 14 III 1565, 14 IV 2372.]
