ChemicalBook > CAS DataBase List > ML335
ML335
- CAS No.825658-06-8
- Chemical Name:ML335
- CBNumber:CB53373069
- Molecular Formula:C15H14Cl2N2O3S
- Formula Weight:373.25
- MOL File:825658-06-8.mol
ML335 Property
- storage temp. -20°
- solubility Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml with warming).
- form solid
- color White
- Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H319-H315-H335
- Precautionary statements P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
ML335 Chemical Properties,Usage,Production
- Description Two-pore domain potassium (K2P) channels of the TREK subfamily regulate neuronal excitability, influence pain, temperature perception and responses to anesthetics. ML-335 (825658-06-8) is a novel, selective TREK-1,2 activator with EC50s of 14.3 and 5.2 μM.1?It represents an important new pharmacological tool for studying the physiology of TREK channels.
- Uses ML335, is a selective activator of both TREK-1 and TREK-2.
- storage Store at +4°C
- References 1) Lolicato?et al.?(2017),?K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site; Nature,?547?364
ML335 Preparation Products And Raw materials
Raw materials
Preparation Products
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825658-06-8, ML335Related Search:
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- 抑制剂
- 药靶配体
- 化合物ML335,10 MM DMSO 溶液
- N-(2,4-二氯苄基)-4-(甲基磺酰氨基)苯甲酰胺
- ML 335,K2P2.1(TREK-1)和K2P10.1(TREK-2)激活剂
- 化合物ML335
- 825658-06-8
- ML335, 10 mM in DMSO
- N-(2,4-Dichlorobenzyl)-4-(methylsulfonamido)benzamide
- Potassium Channel,ML-335,ML 335,ML335,KcsA,Inhibitor,inhibit
- Benzamide, N-[(2,4-dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]-
- TREK-1/2 Activator
- ML335; ML-335; ML 335; TREK-1/2 ACTIVATOR
