Description
Adipamide is a chunky white powder. It is slightly soluble in water and incompatible
with strong oxidising agents. Adipamide on combustion and decomposition produces
hazardous products of toxic fumes of carbon monoxide, carbon dioxide, and nitrogen
oxides. Exposures to adipamide by inhalation, ingestion, or skin absorption cause adverse
health. The symptoms include irritation of the eyes, skin, mucous membranes, and upper
respiratory tract. There is no complete information about the toxicological properties of
the chemical.
Chemical Properties
Adipamide is powder in appearance and slightly soluble in water. It is incompatible with
strong oxidizing agents. On combustion or decomposition, adipamide releases hazardous
products, toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides.
Chemical Properties
Adipamide is white powder and chunks. It is slightly soluble in water and incompatible
with strong oxidizing agents. On combustion and decomposition, adipamide produces
toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides.
Uses
Adipamide has been used in the preparation of bisimidates.
Definition
ChEBI: Adipamide is a fatty amide.
Preparation
Adipamide has been traditionally prepared from the dimethyl ester by treatment with concentrated ammonium hydroxide or by heating the diammonium salt of adipic acid in a stream of ammonia. Other substituted amides can be prepared from amines by the usual synthetic methods.
General Description
Colorless powder.
Air & Water Reactions
Slightly soluble in water .
Reactivity Profile
ADIPAMIDE forms flammable gases with strong reducing agents. A very weak base. Mixing with dehydrating agents such as P2O5 or SOCl2 generates adiponitrile. Combustion generates toxic mixed oxides of nitrogen (NOx).
Health Hazard
Exposures to adipamide cause health disorders such as irritation to the skin, eyes, and
respiratory system. No specifi c adverse health effects have been reported from human
exposure to polyhexamethylene adipamide, except for mechanical irritation of the skin
and eyes caused by particles. Signifi cant skin permeation and systemic toxicity after contact
appears unlikely. The compound is not likely to be hazardous by skin contact, but
cleansing the skin after use is advisable. If molten polymer gets on the skin, cool rapidly with cold water. Workers should not attempt to peel polymer from skin, but consult a
medical unit for treatment of thermal burn.
Health Hazard
Exposures to adipamide by inhalation, ingestion, or skin absorption cause adverse health
effects. The symptoms include irritation of the eyes, skin, mucous membranes, and upper
respiratory tract. There is no complete information about the toxicological properties of
the chemical.
Fire Hazard
The flash point of ADIPAMIDE has not been determined, but ADIPAMIDE is probably combustible.
Safety Profile
Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx,.
storage
Adipamide should be kept stored in a cool, dry place, with containers tightly closed to
prevent moisture absorption and contamination.
storage
Workers should avoid repeated exposures to adipamide. During use, workers should wear
suitable protective clothing, self-contained breathing apparatus, chemical safety goggles,
rubber boots, and heavy rubber gloves.
Precautions
During use and handling of adipamide, workers should wear self-contained breathing
apparatus, rubber boots, heavy rubber gloves, and chemical safety goggles to avoid
splashing of material. A full-face mask respirator provides protection from eye irritation.
Workers should avoid exposure to high concentrations of dust. No specifi c intervention is
indicated as the compound is not likely to be hazardous by inhalation. Consult a physician
if necessary. If exposed to fumes from overheating or combustion, move to fresh air.
Consult a physician if symptoms persist.
