Chemical Properties
Adipamide is powder in appearance and slightly soluble in water. It is incompatible with
strong oxidizing agents. On combustion or decomposition, adipamide releases hazardous
products, toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides.
General Description
Colorless powder.
Reactivity Profile
ADIPAMIDE(628-94-4) forms flammable gases with strong reducing agents. A very weak base. Mixing with dehydrating agents such as P2O5 or SOCl2 generates adiponitrile. Combustion generates toxic mixed oxides of nitrogen (NOx).
Air & Water Reactions
Slightly soluble in water .
Health Hazard
Exposures to adipamide by inhalation, ingestion, or skin absorption cause adverse health
effects. The symptoms include irritation of the eyes, skin, mucous membranes, and upper
respiratory tract. There is no complete information about the toxicological properties of
the chemical.
Health Hazard
Exposures to adipamide cause health disorders such as irritation to the skin, eyes, and
respiratory system. No specifi c adverse health effects have been reported from human
exposure to polyhexamethylene adipamide, except for mechanical irritation of the skin
and eyes caused by particles. Signifi cant skin permeation and systemic toxicity after contact
appears unlikely. The compound is not likely to be hazardous by skin contact, but
cleansing the skin after use is advisable. If molten polymer gets on the skin, cool rapidly with cold water. Workers should not attempt to peel polymer from skin, but consult a
medical unit for treatment of thermal burn.
Fire Hazard
The flash point of this chemical has not been determined, but ADIPAMIDE is probably combustible.
Uses
Adipamide has been used in the preparation of bisimidates.
Definition
ChEBI: Adipamide is a fatty amide.
Preparation
Adipamide has been traditionally prepared from the dimethyl ester by treatment with concentrated ammonium hydroxide or by heating the diammonium salt of adipic acid in a stream of ammonia. Other substituted amides can be prepared from amines by the usual synthetic methods.