ChemicalBook > CAS DataBase List > Azido-PEG2-NHS ester
Azido-PEG2-NHS ester
Azido-PEG2-NHS ester
- CAS No.1312309-64-0
- Chemical Name:Azido-PEG2-NHS ester
- CBNumber:CB53062345
- Molecular Formula:C11H16N4O6
- Formula Weight:300.27
- MOL File:1312309-64-0.mol
Azido-PEG2-NHS ester Property
- solubility Soluble in DMSO, DMF, DCM
- form Liquid
- color Colorless to light yellow
Safety
- HS Code :2942000090
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302+H312+H332-H315-H319-H335
- Precautionary statements P260-P280-P301+P310
Azido-PEG2-NHS ester Chemical Properties,Usage,Production
- Description Azido-PEG2-NHS ester is a click chemistry crosslinker containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
- Uses N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- IC 50 Non-cleavable Linker
Azido-PEG2-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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1312309-64-0, Azido-PEG2-NHS esterRelated Search:
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- peg
- 抑制剂
- 其它
- 有机化学
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- 化合物 N3-PEG2-C2-NHS ESTER
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- 2,5-二氧代吡咯烷-1-基 3-(2-(2-叠氮基乙氧基)乙氧基)丙酸酯
- 3-(2-(2-叠氮乙氧基)乙氧基)丙酸N-琥珀酰亚胺酯
- 叠氮-二聚乙二醇-NHS 酯
- 叠氮-二聚乙二醇-琥珀酰亚胺酯
- 1312309-64-0
- AZIDO-PEG2-NHS
- Azido-PEG2-NHS ester
- N3-PEG2-CH2CH2COONHS/Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
- N3-PEG2-C2-NHS ester
- 2,5-dioxopyrrolidin-1-yl 3-(2-(2-azidoethoxy)ethoxy)propanoate
- N3-PEG2-CH2CH2COONHS
- N3-PEG2-SPA
- Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
- N3-PEG2-Osu
- N3-PEG2-CH2CO2-NHS
- N3-PEG2-CH2CH2COONHS Ester
- Azido-PEG2-CH2CO2-NHS