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Mal-PEG6-COOH

Mal-PEG6-COOH Structure
Mal-PEG6-COOH
  • CAS No.1334177-79-5
  • Chemical Name:Mal-PEG6-COOH
  • CBNumber:CB72603837
  • Molecular Formula:C22H36N2O11
  • Formula Weight:504.53
  • MOL File:1334177-79-5.mol
Mal-PEG6-COOH Property
  • Boiling point 702.5±60.0 °C(Predicted)
  • Density 1.241±0.06 g/cm3(Predicted)
  • pka 4.28±0.10(Predicted)
  • form Solid
  • color Off-white to gray
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338

Mal-PEG6-COOH Chemical Properties,Usage,Production

  • Description Mal-amido-PEG6-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
  • Uses Mal-amido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Mal-PEG6-COOH Preparation Products And Raw materials
Raw materials
Preparation Products
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Mal-PEG6-COOH Spectrum
1334177-79-5, Mal-PEG6-COOHRelated Search:
  • peg
  • Heterobifunctional PEG
  • 抑制剂
  • PEG系列产品-Mal-PEG系列
  • peg衍生物
  • 助剂
  • PEG类产品-MAL-dPEG-Lipoamide
  • C22H36N2O11
  • BMPA-PEG6-酸
  • 化合物 MAL-AMIDO-PEG6-ACID
  • MAL-AMIDO-PEG6-CH2CH2COOH
  • MAL-AMIDO-PEG6-CH2CH3COOH
  • 马来酰亚胺-氨基-六聚乙二醇-羧酸
  • 马来酰亚胺聚乙二醇6羧基
  • 马来酰亚胺-酰胺-PEG6-丙酸
  • 1-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)-3-氧代-7,10,13,16,19,22-六氧杂-4-氮杂二十五烷-25-酸
  • 马来酰亚胺基丙酰胺基六聚乙二醇丙酸
  • 马来酰亚胺-酰胺-六聚乙二醇-丙酸
  • 马来酰亚胺六聚乙二醇羧乙基
  • 马来酰亚胺-酰胺-六聚乙二醇-羧酸
  • 马来酰亚胺丙酰胺-六聚乙二醇-丙酸
  • 双马来酰亚胺-赖氨酸-PEG4-酸
  • 1334177-79-5
  • MAL-dPEG??-acid (QBD-10065)
  • Mal-CH2CH2CONH-PEG6-CH2CH2COOH
  • BMPA-PEG6-Acid
  • 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22-hexaoxa-4-azapentacosan-25-oic acid
  • MAL dPEG6-acid
  • Mal-amido-PEG6-propionic acid
  • 4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-
  • MALEIMIDE-NH-PEG6-
  • Mal-PEG6-COOH
  • Mal-NH-PEG6-COOH
  • MAL-AMIDO-PEG6-COOH
  • Maleimide-PEG6-propionic acid
  • Mal-amido-PEG6-acid
  • MaleiMide-NH-PEG6-CH2CH2COOH

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