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Azido-PEG3-NHS ester

Azido-PEG3-NHS ester Structure
Azido-PEG3-NHS ester
  • CAS No.1245718-89-1
  • Chemical Name:Azido-PEG3-NHS ester
  • CBNumber:CB83062351
  • Molecular Formula:C13H20N4O7
  • Formula Weight:344.32
  • MOL File:1245718-89-1.mol
Azido-PEG3-NHS ester Property
  • solubility Soluble in Water, DMSO, DCM, DMF
  • form Liquid
  • color Colorless to light yellow
Safety
  • HS Code  :2933998090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Azido-PEG3-NHS ester Chemical Properties,Usage,Production

  • Description Azido-PEG3-NHS ester is a azide linker used on click chemistry. The azide group can react with alkyne such as BCN, DBCO, Propargyl group via Click Chemistry to yield a stable triazole linkage. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
  • Uses N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • IC 50 Non-cleavable Linker
Azido-PEG3-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Azido-PEG3-NHS ester Spectrum
1245718-89-1, Azido-PEG3-NHS esterRelated Search:
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  • Azido-PEG3-NHS ester