ChemicalBook > CAS DataBase List > Jaceosidin

Jaceosidin

Jaceosidin Structure
Jaceosidin
  • CAS No.18085-97-7
  • Chemical Name:Jaceosidin
  • CBNumber:CB51515205
  • Molecular Formula:C17H14O7
  • Formula Weight:330.29
  • MOL File:18085-97-7.mol
Jaceosidin Property
  • Melting point 259-260 °C
  • Boiling point 619.0±55.0 °C(Predicted)
  • Density 1.483±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C(protect from light)
  • solubility DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Slightly)
  • form Solid
  • pka 6.47±0.40(Predicted)
  • color Pale Yellow to Light Yellow
  • Stability Hygroscopic
  • LogP 1.300 (est)
  • EWG's Food Scores 1
  • FDA UNII 5U4Y68G678
  • UNSPSC Code 41116107
  • NACRES NA.24
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319
  • Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Jaceosidin Chemical Properties,Usage,Production

  • Uses Jaceosidin exhibits anti-allergic, anti-inflammatory and apoptosis inducing activities.
  • Definition ChEBI: A trihydroxyflavone that is flavone with hydroxy groups at positions 5, 7 and 4' and methoxy groups at positions 3' and 6. Isolated from Salvia tomentosa and Artemisia asiatica, it exhibits anti-allergic, anti-inflammatory and apo tosis inducing activties.
  • in vivo

    Jaceosidin (10 and 20 mg/kg, p.o., once a day for 3 days) blocks carrageenan-induced increase in leukocyte number and protein levels in air pouch exudates in mice[3].
    ? Jaceosidin (10, 20 mg/kg, p.o.) suppresses COX-2 expression and NF-κB activation in mice[3].
    ? Jaceosidin (20 mg/kg, p.o. for 2 hours) reduces hind paw edema volume in rats[3].

    Animal Model:5-week-old male BALB/c mice (23-26 g)[3]
    Dosage:10 and 20 mg/kg
    Administration:P.O. once a day for 3 days
    Result:Decreased the volumes of exudates (inflammatory markers), cell number and protein levels. Inhibited TNF-α by 46.7% and 50.8%, IL-1β by 46.0% and 44.7%, and PGE2 by 21.7% and 16.9%, respectively, at 20 mg/kg. Blocked COX-2 expression and NF-κB activation.
    Animal Model:Male Sprague-Dawley rats (180-200 g)[3]
    Dosage:20 mg/kg
    Administration:P.O., for 2 hour
    Result:Reduced hind paw edema volume by 27.1% at 1 h, and 24.0% at 2 h, respectively.
  • IC 50 Bax; COX-2
Jaceosidin Preparation Products And Raw materials
Raw materials
Preparation Products
Jaceosidin Suppliers
Global(190)Suppliers
  • Supplier：
    Hangzhou ICH Biofarm Co., Ltd
  • Tel：+86-0571-28186870;<br/>+undefined8613073685410
  • Email：sales@ichemie.com
  • Country：China
  • ProdList：1015
  • Advantage：58
  • Supplier：
    Capot Chemical Co.,Ltd.
  • Tel：+86-（0）57185586718<br/>+86-13336195806
  • Email：sales@capot.com
  • Country：China
  • ProdList：29730
  • Advantage：60
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21628
  • Advantage：55
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29858
  • Advantage：58

Related articles

Jaceosidin Spectrum
18085-97-7, JaceosidinRelated Search:
  • standardized herbal extract
  • reference standards from Chinese medicinal herbs (TCM).
  • phytochemical
  • pharmaceutical intermediate
  • chemical reagent
  • 抑制剂
  • 化学试剂
  • 中药标准品，对照品
  • 试剂
  • 药靶配体
  • 新品推荐
  • 标准品，对照品
  • 标准品 -中药标准品
  • 黄酮
  • 标准品-对照品
  • 标准品-中药标准品
  • 分析试剂标准品
  • 医药中间体
  • 对照品
  • 标准品
  • 中药对照品
  • 植物提取物
  • 天然产物
  • 8085-97-7
  • 棕矢车菊素,10 MM DMSO 溶液
  • 棕矢车菊素/HPLC
  • 棕矢车菊素(爵筛奥素)
  • JACOSIDIN
  • 棕矢车菊素对照品,
  • 棕矢车菊素(标准品)
  • 棕矢车菊素(合金欢素,爵筛奥素)
  • 合金欢素
  • 4',5,7-三羟基-3',6-二甲氧基黄酮
  • 4',5,7-三羟基-3',6-二甲氧基苯并吡喃-4-酮
  • 棕矢车菊素、合金欢素
  • 棕矢车菊素
  • 爵筛奥素
  • 18085-97-7
  • Jaceosidin, 10 mM in DMSO
  • Jaceosidin-RM
  • Brown centaurin
  • Jacosidin
  • 4',5,7-Trihydroxy-3',6-dimethoxyflavone 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxychromen-4-one
  • Jaseosidin
  • 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-chromen-4-one
  • 5,7-dihydroxy-2-(4-hydroxy-3-methoxy-phenyl)-6-methoxy-chromen-4-one
  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-
  • 4',5,7-Trihydroxy-3',6-dimethoxyflavone
  • Jacesiolin
  • 6-Hydroxyluteolin 3',6-dimethyl ether
  • 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
  • 3',6-Dimethoxy-4',5,7-trihydroxyflavone
  • JACEOSIDIN

Home

My