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Tacalcitol

Tacalcitol Structure
Tacalcitol
  • CAS No.57333-96-7
  • Chemical Name:Tacalcitol
  • CBNumber:CB4875440
  • Molecular Formula:C27H44O3
  • Formula Weight:416.64
  • MOL File:57333-96-7.mol
Tacalcitol Property
  • Boiling point 565.0±50.0 °C(Predicted)
  • Density 1.06
  • storage temp. Sealed in dry,Store in freezer, under -20°C
  • solubility 20mg/mL in DMSO, 20mg/mL in DMF, 20mg/mL in Ethanol
  • pka 14.43±0.40(Predicted)
  • form Powder
  • color White to off-white
  • biological source synthetic (organic)
  • CAS DataBase Reference 57333-96-7(CAS DataBase Reference)
  • FDA UNII C2W72OJ5ZU
  • ATC code D05AX04
  • UNSPSC Code 12352205
  • NACRES NA.79
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300
  • Precautionary statements P264-P270-P301+P310-P321-P330-P405-P501

Tacalcitol Chemical Properties,Usage,Production

  • Description Tacalcitol, the second vitamin D analog developed as a topical antipsoriatic, was introduced for keratosis, psoriasis, ichthyosis, pityriasis rubra pilaris and palmoplantar pustulosis and keratoderma. It shows improvement in appearance of skin lesions for psoriasis patients without significant side effects. In patients with psoriasis vulgaris, it effectively inhibits keratinocyte growth. Some in vitro studies have shown that tacalcitol inhibits interleukin-1-α-induced granulocyte macrophage colony-stimulating-factor mRNA expression of the human dermal microvascular endothelial cells, which may be involved in mediation of angioproliferation in skin inflammation.
  • Originator Teijin (Japan)
  • Uses Tacalcitol is a synthetic vitamin D3 analog.
  • Definition ChEBI: Tacalcitol is a hydroxy seco-steroid that is calciol which carries hydroxy groups at positions 1S and 24R. It is a vitamin D3 analog which is used for the treatment of psoriasis vulgaris in adults, especially on the scalp. It has a role as an antipsoriatic, a vitamin D receptor agonist and an antineoplastic agent. It is a member of D3 vitamins, a hydroxy seco-steroid, a secondary alcohol and a seco-cholestane. It is functionally related to a calciol.
  • brand name Bonalfa
  • Safety Profile A poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors,
Tacalcitol Preparation Products And Raw materials
Raw materials
Preparation Products
Tacalcitol Suppliers
Global(140)Suppliers
  • Supplier：
    Capot Chemical Co.,Ltd.
  • Tel：+86-（0）57185586718<br/>+86-13336195806
  • Email：sales@capot.com
  • Country：China
  • ProdList：29730
  • Advantage：60
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
Tacalcitol Spectrum
57333-96-7, TacalcitolRelated Search:
  • Vitamin D3 analogs
  • 杂质
  • 杂质对照品
  • 医药化学试剂
  • 化学试剂
  • 前列腺素系列
  • 原料药
  • 化工原料
  • 药物
  • 其它药物
  • 皮肤用药
  • 标准物质/甲醇中他卡西醇
  • 甲醇中他卡西醇
  • TACALCITOL[干冰运输
  • 塔骨化醇
  • 化合物TIPIRACIL HYDROCHLORIDE
  • (1R,3S,Z)-5-((E)-2-((1R,3AS,7AR)-1-((2R,5R)-5-羟基-6-甲基庚-2-基)-7A- 甲基六氢-1H-茚-4(2H)-亚烷基)亚乙基)-4-亚甲基环己烷-1,3-二醇
  • 1,24-二羟基维生素D3
  • 他卡西妥杂质
  • 他卡西醇(干冰运输)
  • -二羟基维生素D3 1.24
  • 他骨化醇, 他卡西醇
  • (1Α,3Β-5Z,7E,24R)-9,10-开环胆甾-5,7,10(19)-三烯-1,3,24-三醇
  • 坦卡三醇
  • 他骨化醇
  • (1A,3B,5Z,7E,24R)-9,10-开环胆甾-5,7,10(19)-三烯-1,3,24-三醇
  • 他卡西醇
  • 他卡西妥
  • 57333-96-7
  • 1,24-Dihydroxyvitamin D<sub>3</sub> solution
  • Tacalcitol in Methanol
  • Tacalcitol(1,24-dihydroxy Vitamin D3)
  • (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
  • Tacalcitol (1,24(R)-Dihydroxyvitamin D3
  • Tacalcitol RS
  • 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-
  • (1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R)-5-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
  • TacalcitolQ: What is Tacalcitol Q: What is the CAS Number of Tacalcitol Q: What is the storage condition of Tacalcitol Q: What are the applications of Tacalcitol
  • 1ALPHA,24(R)-DIHYDROXYVITAMIND3
  • TV 02
  • PRI 2191
  • Curatoderm
  • Bonalfa
  • 9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol, (1a,3b,5Z,7E,24R)- (9CI)
  • 1a,24R-Dihydroxyvitamin D3
  • 1a,24(R)-Dihydroxyvitamin D3
  • 1a,24(R)-Dihydroxycholecalciferol
  • trans-Calcitriol
  • 1-alpha-3-beta-5E,7E,24R)-9,10-Secocholesta-5,7,10,19-triene-1,3,24-triol
  • Tacalcitol
  • 4-methylene-5Z-[2E-[(3aS)-octahydro-1R-[4R-hydroxy-1R,5-dimethylhexyl]-7aR-methyl-4H-inden-4-ylidene]ethylidene]-1R,3S-cyclohexanediol
  • 1α,24(R)-Dihydroxycholecalciferol
  • Tacalcital
  • (1α,3β,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol
  • C12919
  • (1a,3b,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol
  • 1α,24R-Dihydroxyvitamin D3
  • 1α,24(R)-Dihydroxyvitamin D3

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