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VitaMin D4

VitaMin D4 Structure
VitaMin D4
  • CAS No.511-28-4
  • Chemical Name:VitaMin D4
  • CBNumber:CB3104866
  • Molecular Formula:C28H46O
  • Formula Weight:398.66
  • MOL File:511-28-4.mol
VitaMin D4 Property
  • Melting point 83-86 °C(lit.)
  • alpha D18 +89.3° (c = 0.47 in acetone)
  • Boiling point 504.9±29.0 °C(Predicted)
  • Density 0.96
  • storage temp. 2-8°C
  • solubility Soluble in Chloroform
  • form Powder
  • pka 14.74±0.20(Predicted)
  • color Off-white to light yellow
  • Stability Hygroscopic, Temperature Sensitive
  • CAS DataBase Reference 511-28-4(CAS DataBase Reference)
  • FDA 21 CFR 172.380; 184.1950; 104.20; 107.10; 107.100
  • EWG's Food Scores 1-4
  • FDA UNII KN41X73N6C
  • NCI Dictionary of Cancer Terms vitamin D
  • NCI Drug Dictionary vitamin D
  • ATC code A11CC05,A11CC55
  • UNSPSC Code 12352200
  • NACRES NA.79
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301+H311-H330-H372
  • Precautionary statements P280-P301+P310+P330-P302+P352+P312-P304+P340+P310-P314
VitaMin D4 Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 88815
  • Product name : 22,23-Dihydroergocalciferol
  • Purity: ≥97.0% (HPLC)
  • Packaging: 1MG
  • Price: ₹22602.6
  • Updated: 2022/06/14
  • Buy: Buy

VitaMin D4 Chemical Properties,Usage,Production

  • Description Derived from cholesterol, vitamin D is biosynthesized from its prohormone cholecalciferol (D3), the product of solar ultraviolet irradiation of 7-dehydrocholesterol in the skin. In 1966, it was first recognized that vitamin D must undergo activation via two oxidative metabolic steps. The first oxidation to 25-hydroxycholecalciferol (25(OH)D3: calcifediol; Calderol) occurs in the endoplasmic reticulum of the liver and is catalyzed by vitamin D 25-hydroxylase. This activation step is not regulated by plasma calcium concentrations. The major circulating form (10–80 μg/mL) is 25(OH)D3, which also is the primary storage form of vitamin D.
  • Chemical Properties Pale Yellow Oil
  • Uses Vitamin D4 is the active analogue of Vitamin D.
  • Definition ChEBI: Vitamin D4 is it is present in mushrooms. It has a role as a fungal metabolite. It is a vitamin D and a seco-ergostane.
  • Biological Functions Sterol-specific cytoplasmic receptor proteins (vitamin D receptor) mediate the biological action of vitamin D. The active hormone is transported from the cytoplasm to the nucleus via the vitamin D receptor, and as a result of the interaction of the hormone with target genes, a variety of proteins are produced that stimulate the transport of calcium in each of the target tissues Active vitamin D works in concert with PTH to enhance active intestinal absorption of calcium, to stimulate bone resorption, and to prohibit renal excretion of calcium. If serum calcium or 1,25-calcitriol concentrations are elevated, then vitamin D 24-hydroxylase (in renal mitochondria) is activated to oxidize 25(OH)D3 to inactive 24,25-dihydroxy-cholecalciferol and to further oxidize active vitamin D to the inactive 1,24,25-trihydroxylated derivative. Both the 1,24,25-trihydroxylated and the 24,25-dihydroxylated products have been found to suppress PT H secretion as well. The biosynthesis of vitamin D is tightly regulated based on the serum concentrations of calcium, phosphate, PTH, and active vitamin D.
VitaMin D4 Preparation Products And Raw materials
Raw materials
Preparation Products
VitaMin D4 Suppliers
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VitaMin D4 Spectrum
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