ChemicalBook > CAS DataBase List > Ciprofloxacin hydrochloride hydrate
Ciprofloxacin hydrochloride hydrate
Ciprofloxacin hydrochloride hydrate
- CAS No.86393-32-0
- Chemical Name:Ciprofloxacin hydrochloride hydrate
- CBNumber:CB4740508
- Molecular Formula:C17H21ClFN3O4
- Formula Weight:385.82
- MOL File:86393-32-0.mol
Ciprofloxacin hydrochloride hydrate Property
- Melting point 318-320 °C
- RTECS VB1993800
- storage temp. Inert atmosphere,Store in freezer, under -20°C
- solubility Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol, practically insoluble in acetone, in ethyl acetate and in methylene chloride.
- form Solid
- color White to Light yellow
- PH pH (25g/l, 25℃) 3.0~4.5
- Water Solubility Soluble in water (35mg/ml).
- Merck 14,2314
- InChIKey DIOIOSKKIYDRIQ-UHFFFAOYSA-N
- CAS DataBase Reference 86393-32-0(CAS DataBase Reference)
- FDA UNII 4BA73M5E37
- UNSPSC Code 41116107
- NACRES NA.24
Safety
- WGK Germany :3
- HazardClass :IRRITANT
- HS Code :2933595960
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
Ciprofloxacin hydrochloride hydrate Price
More Price(8)
- Brand: Sigma-Aldrich(India)
- Product number: PHR1044
- Product name : Ciprofloxacin HCl
- Purity: Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging: 1G
- Price: ₹9493.53
- Updated: 2022/06/14
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: C2227
- Product name : Ciprofloxacin Hydrochloride Monohydrate
- Purity:
- Packaging: 5G
- Price: ₹3500
- Updated: 2022/05/26
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: C2227
- Product name : Ciprofloxacin Hydrochloride Monohydrate
- Purity:
- Packaging: 25G
- Price: ₹7600
- Updated: 2022/05/26
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: C2227
- Product name : Ciprofloxacin Hydrochloride Monohydrate
- Purity:
- Packaging: 100G
- Price: ₹12000
- Updated: 2022/05/26
- Buy: Buy
- Brand: SRL
- Product number: 78079
- Product name : Ciprofloxacin Hydrochloride Hydrate (CPFX), 98-102%
- Purity:
- Packaging: 1Gms
- Price: ₹440
- Updated: 2022/05/26
- Buy: Buy
Ciprofloxacin hydrochloride hydrate Chemical Properties,Usage,Production
- Chemical Properties Pale yellow, crystalline, slightly hygroscopic powder.
- Uses Fluoroquinolone antibacterial.
- Uses Ciprofloxacin hydrochloride has been suggested as a treatment for a wide range of infections caused by susceptible organisms including infections of urinary, respiratory, and gastrointestinal tracts, gonorrhoea and septicaemia. Nalidixic acid analogue.
- Application Ciprofloxacin hydrochloride hydrate is a broad-spectrum antibiotic that inhibits bacterial DNA gyrase and blocks DNA synthesis and replication, resulting in bacterial death. It has strong antibacterial activity against Escherichia coli, Klebsiella and other Enterobacteriaceae; the antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae is better than norfloxacin and pefloxacin.
- Definition ChEBI: The monohydrate form of ciprofloxacin monohydrochloride.
- brand name Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).
- General Description Ciprofloxacin HCl is a fluoroquinolone antibiotic agent, which shows a broad spectrum of antibacterial activity against gram positive and gram negative bacteria.
- in vitro Ciprofloxacin (hydrochloride monohydrate) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. Ciprofloxacin (hydrochloride monohydrate) (CIP) shows potent activity against Y. pestis with MIC 90 of 0.03 μg/mL.
- in vivo Ciprofloxacin (hydrochloride monohydrate) (1 mg/L) induces glutathione-S-transferase (GST) activity, in contrast with inhibited GST and Catalase (CAT) of larvae exposed to enrofloxacin. Ciprofloxacin (hydrochloride monohydrate) (≥10 μg/L) is ecotoxic for development, growth, detoxifying, and oxidative stress enzymes in anuran amphibian larvae. In a murine model of pneumonic plague, Ciprofloxacin (hydrochloride monohydrate) (30 mg/kg, i.p.) results in a drug exposure which is similar to the drug exposure observed in human following a 500 mg dose of oral Ciprofloxacin (hydrochloride monohydrate). Intraperitoneal Ciprofloxacin (hydrochloride monohydrate) reduces the lung bacterial load compare to controls treated with intraperitoneal PBS.
Ciprofloxacin hydrochloride hydrate Preparation Products And Raw materials
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- C17H18FN3O3HCl
- C17H21ClFN3O4
- C17H18FN3O3ClHH2O
- C17H10FN3O3
- C17H18FN3O3HClH2O
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