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Nicarbazin

CAS No.330-95-0
Chemical Name:Nicarbazin
CBNumber:CB4734477
Molecular Formula:C19H18N6O6
Formula Weight:426.38
MOL File:330-95-0.mol

Nicarbazin Property

Melting point 265-267 °C
Boiling point 541.86°C (rough estimate)
Density 1.4663 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. 0-6°C
solubility DMSO: soluble0.5mg/mL
form Solid
color Yellow to Dark Yellow
FDA 21 CFR 556.445; 558.366
FDA UNII 11P9NUA12U
EPA Substance Registry System Nicarbazin (330-95-0)
UNSPSC Code 51102829
NACRES NA.85

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36
WGK Germany :3
RTECS :FE0900000
HS Code :38249099
Hazardous Substances Data :330-95-0(Hazardous Substances Data)

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338

Nicarbazin Price More Price(2)

Brand: Sigma-Aldrich(India)
Product number: N3905
Product name : Nicarbazin
Purity:
Packaging: 100G
Price: ₹6833.03
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 32409
Product name : Nicarbazin
Purity: VETRANAL?, analytical standard
Packaging: 100MG
Price: ₹11626.88
Updated: 2022/06/14
Buy: Buy

Nicarbazin Chemical Properties,Usage,Production

Chemical Properties Nicarbazin is a light yellow crystalline powder, odorless. Melting point 265-275°C (decomposition). Non-hygroscopic, insoluble in water, ethanol, chloroform and ether, slightly soluble in dimethylformamide. It decomposes slowly when it is ground with water, and decomposes faster in dilute acid.
Uses Nicarbazin, is a coccidiostat, which is an antiprotozoal agent that acts upon Coccidia parasites.It is a contraceptive for resident Canada geese and waterfowl. It is used to study avian reproduction and is used to interfere with the formation of the vitelline (yolk) membrane in bird eggs. It has been used to study how delivery method can effect plasma levels of 4,4′-dinitrocarbanilide (DNC), which is the active anticoccidial component of Nicarbazin.
Definition ChEBI: Nicarbazin is an organic molecular entity. It is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. A coccidiostat for poultry.
Biochem/physiol Actions Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug. It affects avian reproduction by reducing egg production, egg weight, and egg hatchability. The mechanism of action of Nicarbazin is unknown.
Mode of action Nicarbazin interferes with the formation of the vitelline membrane, separating the egg yolk and egg white. The exact mode of action is unknown, although it is thought nicarbazin interferes with cholesterol metabolism in the formation of the membrane. Eggs from treated birds are described as mottled in appearance, reflecting a porous vitelline membrane. The effect on hatchability is a function of time and dose and the effect is reversible.