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RONIDAZOLE

Brand Name(s)
RONIDAZOLE Structure
RONIDAZOLE
  • CAS No.7681-76-7
  • Chemical Name:RONIDAZOLE
  • CBNumber:CB4269522
  • Molecular Formula:C6H8N4O4
  • Formula Weight:200.15
  • MOL File:7681-76-7.mol
RONIDAZOLE Property
  • Melting point 167-169°
  • Boiling point 337.86°C (rough estimate)
  • Density 1.5359 (rough estimate)
  • refractive index 1.6500 (estimate)
  • storage temp. −20°C
  • solubility DMSO (Slightly), Methanol (Slightly, Heated)
  • pka 1.2(at 25℃)
  • form Solid
  • color Pale Yellow
  • InChI InChI=1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)
  • InChIKey PQFRTXSWDXZRRS-UHFFFAOYSA-N
  • SMILES C1(COC(=O)N)=NC=C([N+]([O-])=O)N1C
  • FDA UNII E01R4M1063
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • Safety Statements  :22-24/25
  • WGK Germany  :2
  • RTECS  :NI6803000
  • HS Code  :29332900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P280-P305+P351+P338
RONIDAZOLE Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: R7635
  • Product name : Ronidazole
  • Purity: analytical standard
  • Packaging: 5G
  • Price: ₹3442.35
  • Updated: 2022/06/14
  • Buy: Buy

RONIDAZOLE Chemical Properties,Usage,Production

  • Brand Name(s) Flagyl and generic
  • Uses antibacterial
  • Uses Antimicrobial.
  • Definition ChEBI: Ronidazole is a carbamate ester that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by methyl and (carbamoyloxy)methyl groups, respectively. An antiprotozoal agent, it is used in veterinary medicine for the treatment of histomoniasis and swine dysentery. It has a role as an antiprotozoal drug and an antiparasitic agent. It is a member of imidazoles, a carbamate ester and a C-nitro compound.
  • Veterinary Drugs and Treatments Ronidazole is a nitroimidazole antibiotic/antiparasitic drug that appears to be useful in treating Tritrichomonas foetus infections in cats. The drug is not commercially available in the USA and must be compounded from bulk powder by a compounding pharmacy. The drug is also used for treating Trichomonas infections in nonfood animal birds.
  • in vivo


    Pharmacokinetic Analysis in six cats[3]

    Dose (mg/kg) Time (h) AUClast Cmax (ng/mL)
    Drug administrationDose (mg/kg)T1/2 (K) (h)C0 (μg/mL)AUC 0-∞ (h?μg/m)Vd or Vd/F (mL/kg)Clearance or CL/F (h)MRT (h)Tmax (h)Cmax (μg/m)F (%)
    i.v.9.1759.8013.27187.307000.8214.14NANANA
    p.o.28.2310.50NA566.987700.84NA1.0235.3799.64
    Animal Model:CDI mice model[2]
    Dosage:1 mg/kg, 10mg/kg
    Administration:Oral gavage
    Result:Both 1 mg/kg and 10 mg/kg Ronidazole protected 60% of mice from infection
RONIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
RONIDAZOLE Suppliers
Global(235)Suppliers
  • Supplier：
    airuikechemical co., ltd.
  • Tel：+86-18353166132<br/>+86-18353166132
  • Email：sales02@airuikechemical.com
  • Country：China
  • ProdList：983
  • Advantage：58
  • Supplier：
    Xiamen AmoyChem Co., Ltd
  • Tel：+86-86-5926051114<br/>+8615060885618
  • Email：sales@amoychem.com
  • Country：China
  • ProdList：6383
  • Advantage：58

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  • C6H8N4O4
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