ChemicalBook > CAS DataBase List > 4-Cholesten-3-one
4-Cholesten-3-one
4-Cholesten-3-one
- CAS No.601-57-0
- Chemical Name:4-Cholesten-3-one
- CBNumber:CB3222827
- Molecular Formula:C27H44O
- Formula Weight:384.64
- MOL File:601-57-0.mol
4-Cholesten-3-one Property
- Melting point 79-82 °C
- alpha 92.5 º (c=2, CHCl3)
- Boiling point 451.27°C (rough estimate)
- Density 0.9717 (rough estimate)
- refractive index 1.5100 (estimate)
- storage temp. -20°C
- solubility Chloroform (Sparingly), Methanol (Slightly, Heated)
- form Solid
- color White to Off-White
- optical activity [α]23/D +91.0°, c = 2 in chloroform
- Water Solubility <0.5 g/L
- BRN 4707774
- Stability Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference 601-57-0(CAS DataBase Reference)
- EWG's Food Scores 1
- FDA UNII 7T94NHD99C
- NIST Chemistry Reference Cholest-4-en-3-one(601-57-0)
- EPA Substance Registry System Cholest-4-en-3-one (601-57-0)
- UNSPSC Code 12352211
- NACRES NA.25
Safety
- Hazard Codes :Xi
- Risk Statements :36/37/38
- Safety Statements :22-24/25-36-26
- WGK Germany :3
- RTECS :FZ7700000
- TSCA :Yes
- HS Code :29142900
-
NFPA 704:
1 1 0
- Symbol(GHS)
- Signal word
- Hazard statements H413
- Precautionary statements
4-Cholesten-3-one Price
More Price(3)
- Brand: Sigma-Aldrich(India)
- Product number: 188174
- Product name : (+)-4-Cholesten-3-one
- Purity: 98%
- Packaging: 1G
- Price: ₹1948.5
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 188174
- Product name : (+)-4-Cholesten-3-one
- Purity: 98%
- Packaging: 10G
- Price: ₹7144.5
- Updated: 2022/06/14
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: C1366
- Product name : (+)-4-Cholesten-3-one
- Purity: min. 95.0 %
- Packaging: 5G
- Price: ₹5900
- Updated: 2022/05/26
- Buy: Buy
4-Cholesten-3-one Chemical Properties,Usage,Production
- Description Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.
- Chemical Properties white to light yellow crystals or powder
- Uses 4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.
- Definition ChEBI: Cholest-4-en-3-one is a cholestanoid that is cholest-4-ene substituted by an oxo group at position 3. It has a role as a human metabolite and a plant metabolite. It is a cholestanoid and a 3-oxo-Delta(4) steroid.
- General Description Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.
4-Cholesten-3-one Preparation Products And Raw materials
Raw materials
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601-57-0, 4-Cholesten-3-oneRelated Search:
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- Biochemistry
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- 药靶配体
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- 脂类
- Steroids (Others)
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- Asymmetric Synthesis
- Chiral Building Blocks
- Complex Molecules
- (8S,9S,10R,13R,14S,17R)-10,13-二甲基-17-((R-6-6-甲基庚-2-基)-6,7,8,9,10,11,12,13,14,15,16,17-十二氢-1H-环戊二烯并[A]菲-3(2H)-酮
- PERFEMIKER]4-胆甾烯-3-酮,95%
- 胆甾酮(2,2,4,6,6-D5,98%)
- 4-胆甾烯-3-酮 标准品
- Δ4-CHOLESTEN-3-ONE
- 胆甾-4-烯-3-酮
- 膽甾烯酮
- 4-胆甾烯-3-酮, 98+%
- (+)-4-胆甾烯-3-酮
- 正-4-胆甾烯-3-酮
- 4-胆甾烯-3-酮
- 601-57-0
- (+)-3-Oxo-4-Cholestene
- (+)-4-Cholesten-3-one
- (+)-4-Cholesten-3-one >
- 4-Cholestene-3-one
- (1S,2R,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
- 4-CHOLESTEN-3-ONE;CHOLESTENONE
- (+)-4-Cholesten-3-one 98%
- (8S,9S,10R,13R,14S,17R)-10,13-diMethyl-17-((R)-6-Methylheptan-2-yl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
- Cholestane-4-ene-3-one
- (20R)-Cholesta-4-ene-3-one
- delta(sup 4)-Cholestenone
- 3-Keto-4-cholestene, 3-Oxo-4-cholestene, 4-Cholesten-3-one
- 3-Keto-4-cholestene, 3-Oxo-4-cholestene
- (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
- 4-CHOLESTEN-3-ONE, 98+%
- 10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
- (8S,9S,10R,13R,14S,17R)-17-((R)-1,5-DIMETHYL-HEXYL)-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
- delta4-Cholesten-3-one
- cholest-4-en-3-one
- 4-Cholestenone
- 3-Oxocholest-4-ene
- CHOLESTENONE
- CHOLEST-4-ENE-3-ONE
- 3-OXO-4-CHOLESTENE
- 3-KETO-4-CHOLESTENE
- 4-CHOLESTEN-3-ONE
- 17-(1,5-DIMETHYLHEXYL)-10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE
- 17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecah