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4-Cholesten-3-one

4-Cholesten-3-one Structure
4-Cholesten-3-one
  • CAS No.601-57-0
  • Chemical Name:4-Cholesten-3-one
  • CBNumber:CB3222827
  • Molecular Formula:C27H44O
  • Formula Weight:384.64
  • MOL File:601-57-0.mol
4-Cholesten-3-one Property
  • Melting point 79-82 °C
  • alpha 92.5 º (c=2, CHCl3)
  • Boiling point 451.27°C (rough estimate)
  • Density 0.9717 (rough estimate)
  • refractive index 1.5100 (estimate)
  • storage temp. -20°C
  • solubility Chloroform (Sparingly), Methanol (Slightly, Heated)
  • form Solid
  • color White to Off-White
  • optical activity [α]23/D +91.0°, c = 2 in chloroform
  • Water Solubility <0.5 g/L
  • BRN 4707774
  • Stability Stable. Incompatible with strong oxidizing agents.
  • CAS DataBase Reference 601-57-0(CAS DataBase Reference)
  • EWG's Food Scores 1
  • FDA UNII 7T94NHD99C
  • NIST Chemistry Reference Cholest-4-en-3-one(601-57-0)
  • EPA Substance Registry System Cholest-4-en-3-one (601-57-0)
  • UNSPSC Code 12352211
  • NACRES NA.25
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :22-24/25-36-26
  • WGK Germany  :3
  • RTECS  :FZ7700000
  • TSCA  :Yes
  • HS Code  :29142900
  • NFPA 704:
    1
    1 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements H413
  • Precautionary statements
4-Cholesten-3-one Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: 188174
  • Product name : (+)-4-Cholesten-3-one
  • Purity: 98%
  • Packaging: 1G
  • Price: ₹1948.5
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 188174
  • Product name : (+)-4-Cholesten-3-one
  • Purity: 98%
  • Packaging: 10G
  • Price: ₹7144.5
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: C1366
  • Product name : (+)-4-Cholesten-3-one
  • Purity: min. 95.0 %
  • Packaging: 5G
  • Price: ₹5900
  • Updated: 2022/05/26
  • Buy: Buy

4-Cholesten-3-one Chemical Properties,Usage,Production

  • Description Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.
  • Chemical Properties white to light yellow crystals or powder
  • Uses 4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.
  • Definition ChEBI: Cholest-4-en-3-one is a cholestanoid that is cholest-4-ene substituted by an oxo group at position 3. It has a role as a human metabolite and a plant metabolite. It is a cholestanoid and a 3-oxo-Delta(4) steroid.
  • General Description Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.
4-Cholesten-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
4-Cholesten-3-one Suppliers
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4-Cholesten-3-one Spectrum
601-57-0, 4-Cholesten-3-oneRelated Search:
  • Biochemistry
  • Steroids (Others)
  • Steroids
  • 抑制剂
  • 杂质-胆固醇杂质
  • 有机原料-酮
  • 药靶配体
  • 有机中间体
  • 脂类
  • Steroids (Others)
  • Steroids
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Complex Molecules
  • (8S,9S,10R,13R,14S,17R)-10,13-二甲基-17-((R-6-6-甲基庚-2-基)-6,7,8,9,10,11,12,13,14,15,16,17-十二氢-1H-环戊二烯并[A]菲-3(2H)-酮
  • PERFEMIKER]4-胆甾烯-3-酮,95%
  • 胆甾酮(2,2,4,6,6-D5,98%)
  • 4-胆甾烯-3-酮 标准品
  • Δ4-CHOLESTEN-3-ONE
  • 胆甾-4-烯-3-酮
  • 膽甾烯酮
  • 4-胆甾烯-3-酮, 98+%
  • (+)-4-胆甾烯-3-酮
  • 正-4-胆甾烯-3-酮
  • 4-胆甾烯-3-酮
  • 601-57-0
  • (+)-3-Oxo-4-Cholestene
  • (+)-4-Cholesten-3-one
  • (+)-4-Cholesten-3-one &gt
  • 4-Cholestene-3-one
  • (1S,2R,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
  • 4-CHOLESTEN-3-ONE;CHOLESTENONE
  • (+)-4-Cholesten-3-one 98%
  • (8S,9S,10R,13R,14S,17R)-10,13-diMethyl-17-((R)-6-Methylheptan-2-yl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • Cholestane-4-ene-3-one
  • (20R)-Cholesta-4-ene-3-one
  • delta(sup 4)-Cholestenone
  • 3-Keto-4-cholestene, 3-Oxo-4-cholestene, 4-Cholesten-3-one
  • 3-Keto-4-cholestene, 3-Oxo-4-cholestene
  • (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • 4-CHOLESTEN-3-ONE, 98+%
  • 10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • (8S,9S,10R,13R,14S,17R)-17-((R)-1,5-DIMETHYL-HEXYL)-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
  • delta4-Cholesten-3-one
  • cholest-4-en-3-one
  • 4-Cholestenone
  • 3-Oxocholest-4-ene
  • CHOLESTENONE
  • CHOLEST-4-ENE-3-ONE
  • 3-OXO-4-CHOLESTENE
  • 3-KETO-4-CHOLESTENE
  • 4-CHOLESTEN-3-ONE
  • 17-(1,5-DIMETHYLHEXYL)-10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE
  • 17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecah