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L-HOMOCARNOSINE FREE BASE

L-HOMOCARNOSINE FREE BASE Structure
L-HOMOCARNOSINE FREE BASE
  • CAS No.3650-73-5
  • Chemical Name:L-HOMOCARNOSINE FREE BASE
  • CBNumber:CB2503590
  • Molecular Formula:C10H16N4O3
  • Formula Weight:240.26
  • MOL File:3650-73-5.mol
L-HOMOCARNOSINE FREE BASE Property
  • Boiling point 646.9±55.0 °C(Predicted)
  • Density 1.327±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility DMF: 30 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
  • form A solid
  • pka 2.99±0.10(Predicted)
  • FDA UNII M8L4BH36SC
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P264-P270-P301+P312-P330-P501

L-HOMOCARNOSINE FREE BASE Chemical Properties,Usage,Production

  • Uses Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects[1].Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation[2].
  • Definition ChEBI: A homocarnosine that has S configuration.
  • IC 50 Human Endogenous Metabolite
  • References [1] O A Petroff, et al. Vigabatrin increases human brain homocarnosine and improves seizure control. Ann Neurol. 1998 Dec;44(6):948-52. DOI:10.1002/ana.410440614
    [2] Thanutchaporn Kumrungsee, et al. Dietary GABA induces endogenous synthesis of a novel imidazole peptide homocarnosine in mouse skeletal muscles. Amino Acids. 2020 May;52(5):743-753. DOI:10.1007/s00726-020-02848-x
L-HOMOCARNOSINE FREE BASE Preparation Products And Raw materials
Raw materials
Preparation Products
L-HOMOCARNOSINE FREE BASE Suppliers
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L-HOMOCARNOSINE FREE BASE Spectrum
3650-73-5, L-HOMOCARNOSINE FREE BASERelated Search:
  • 抑制剂
  • 杂环
  • 芳烃衍生物
  • 4-氨基丁酸-HIS
  • 高肌肽
  • L-高肌肽
  • 3650-73-5
  • [H659245] HomocarnosineTFA
  • NSC-92522
  • NSC92522
  • NSC 92522
  • L-Histidine, N-(4-aMino-1-oxobutyl)-
  • γAbu-L-His-OH
  • Nα-(4-Aminobutyryl)histidine
  • γ-Aminobutyryl-L-histidine
  • N-(4-amino-1-oxobutyl)-L-Histidine
  • L-HOMOCARNOSINE FREE BASE

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