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HC TOXIN

HC TOXIN Structure
HC TOXIN
  • CAS No.83209-65-8
  • Chemical Name:HC TOXIN
  • CBNumber:CB2460604
  • Molecular Formula:C21H32N4O6
  • Formula Weight:436.51
  • MOL File:83209-65-8.mol
HC TOXIN Property
  • Boiling point 819.2±65.0 °C(Predicted)
  • Density 1.28±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility DMSO: 10 mg/ml; Methanol: 10 mg/ml
  • pka 13.33±0.70(Predicted)
  • form lyophilized powder
  • color Off-white to light yellow
  • FDA UNII 17NL0QLS6P
  • UNSPSC Code 12352202
Safety
  • Hazard Codes  :T
  • Risk Statements  :25
  • Safety Statements  :45
  • RIDADR  :UN 2811 6.1 / PGIII
  • WGK Germany  :3
  • NFPA 704:
    0
    4 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300
  • Precautionary statements P264-P301+P310
HC TOXIN Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: H7270
  • Product name : HC toxin from Helminthosporium carbonum
  • Purity: lyophilized powder
  • Packaging: 5MG
  • Price: ₹71196.03
  • Updated: 2022/06/14
  • Buy: Buy

HC TOXIN Chemical Properties,Usage,Production

  • Description HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.
  • Uses HC Toxin is an HDAC inhibitor. Cyclic tetrapeptide[1] fungal toxin selectively toxic to plants with susceptible host genotype (2)
  • Definition ChEBI: A homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues.
  • Biochem/physiol Actions Cyclic tetrapeptide fungal toxin selectively toxic to plants with susceptible host genotype.
HC TOXIN Preparation Products And Raw materials
Raw materials
Preparation Products
HC TOXIN Suppliers
Global(65)Suppliers
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
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  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
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  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
  • Country：United States
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  • Supplier： Sigma-Aldrich
  • Tel：021-61415566<br/>800-8193336
  • Email：orderCN@merckgroup.com
  • Country：China
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  • Supplier： BOC Sciences
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  • Email：info@bocsci.com
  • Country：USA
  • ProdList：0
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HC TOXIN Spectrum
83209-65-8, HC TOXINRelated Search:
  • Toxins and Venoms
  • Mold
  • Cell Signaling and Neuroscience
  • 抑制剂
  • 药靶配体
  • 医药原料
  • C21H32N4O6
  • HC TOXIN,HISTONE DEACETYLASE (HDAC)抑制剂
  • 玉米圆斑病菌毒素
  • HC毒素
  • 83209-65-8
  • HC toxin from <i>Helminthosporium carbonum</i>
  • HC Toxin, histone deacetylase (HDAC) inhibitor
  • (3S,6R,9S,12R)-6,9-dimethyl-3-[6-[(2S)-oxiran-2-yl]-6-oxohexyl]-1,4,7,10-tetrazabicyclo[10.3.0]pentadecane-2,5,8,11-tetrone
  • HC TOXIN
  • CYCLO-(D-PRO-L-ALA-D-ALA-L-2-AMINO-8-OXO-9,10-EPOXYDECANOIC ACID)
  • Cyclo(L-alanyl-D-alanyl-8-oxiranyl-8-oxo-L-2-aminooctanoyl-D-prolyl), (S)-
  • Cyclo(L-alanyl-D-alanyl-(alphas,2S)-alpha-amino-eta-oxooxiraneoctanoyl-D-prolyl)
  • Cyclo(aoe-Pro-Ala-ala)
  • Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine)
  • Cyclic(L-alanyl-D-alanyl-eta-oxo-L-alpha-aminooxiraneoctanoyl-D-prolyl)
  • Toxin I
  • HC toxin I
  • Cyclo[L-Ala-D-Ala-[(2S)-2-amino*-8-oxo-8-oxiranyloctanoyl]-D-Pro-]
  • Cyclo[D-Pro-L-Ala-D-Ala-2-(6-oxo-6-oxiranylhexyl)-L-Gly-]
  • HC TOXIN FROM HELMINTHOSPORIUM CARBONUM

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