ChemicalBook > CAS DataBase List > 2'-O-Methylguanosine

2'-O-Methylguanosine

2'-O-Methylguanosine Structure
2'-O-Methylguanosine
  • CAS No.2140-71-8
  • Chemical Name:2'-O-Methylguanosine
  • CBNumber:CB2276641
  • Molecular Formula:C11H15N5O5
  • Formula Weight:297.27
  • MOL File:2140-71-8.mol
2'-O-Methylguanosine Property
  • Melting point 227-231°C (dec.)
  • Density 1.98±0.1 g/cm3(Predicted)
  • storage temp. Keep in dark place,Inert atmosphere,2-8°C
  • solubility Aqueous Base (Slightly), DMSO (Slightly),
  • pka 9?+-.0.20(Predicted)
  • form Powder
  • color White to Off-white
  • λmax 256 (pH 1)；258 (pH 11)
  • InChI InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1
  • InChIKey OVYNGSFVYRPRCG-KQYNXXCUSA-N
  • SMILES OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](OC)[C@@H]1O
  • CAS DataBase Reference 2140-71-8(CAS DataBase Reference)
  • FDA UNII W722H4PA1S
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a
2'-O-Methylguanosine Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: M2318
  • Product name : 2'-O-Methylguanosine
  • Purity: 
  • Packaging: 200MG
  • Price: ₹5200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: M2318
  • Product name : 2'-O-Methylguanosine
  • Purity: 
  • Packaging: 1G
  • Price: ₹20800
  • Updated: 2022/05/26
  • Buy: Buy

2'-O-Methylguanosine Chemical Properties,Usage,Production

  • Description 2''-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase, using S-adenosyl-L-methionine (Item Nos. 16376 | 13956) as a substrate. Through its interaction with other modified nucleosides, 2''-O-methylguanosine is thought to stabilize the structure of the tRNA. 2''-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2''-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells.
  • Chemical Properties White Solid
  • Uses Guanosine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
  • Definition ChEBI: Guanosine with the hydrogen on the hydroxyl at position C-2' substituted with a methyl group.
  • Synthesis 8-Thio-2'-O-methylguanosine (1 mmole) is dissolved in water and the solution is heated at reflux with Raney nickel for 6 h. The product is isolated by passing the solution through a short pad of celite and is further crystallizing to afford 2'-O-methylguanosine.
    2'-O-Methylguanosine
2'-O-Methylguanosine Preparation Products And Raw materials
Raw materials
Preparation Products
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2'-O-Methylguanosine Spectrum
2140-71-8, 2'-O-MethylguanosineRelated Search:
  • Nucleosides-2'-OMe Nucleosides
  • Modified（deoxy）nucleoside
  • Nucleosides
  • Heterocycles
  • Carbohydrates & Derivatives
  • Bases & Related Reagents
  • Nucleotides
  • 化工原料及中间体
  • 医药化工类
  • 修饰核苷
  • 甲氧基
  • 抑制剂
  • 化学试剂
  • 有机化合物
  • 生化试剂
  • 核苷，核苷酸，寡核苷酸
  • C11H15N5O5H2O
  • C11H15N5O5xH2O
  • 2'-甲氧基鸟苷,10 MM DMSO 溶液
  • 2-甲氧基苷
  • 2''-O-甲基鸟苷
  • 2-氨基-9-((2R,3R,4R,5R)-4-羟基-5-(羟甲基)-3-甲氧基四氢呋喃-2-基)-1H-嘌呤-6(9H)-酮
  • 2'-甲氧基鸟苷(2'-OME-RG)
  • 2'-O-甲基鸟苷水合物
  • 2'-甲氧基鸟苷
  • 2'-O-甲基鸟苷
  • 2140-71-8
  • 2&#8242,-O-Me-Guo
  • 2’-OMe-Guanosine, 10 mM in DMSO
  • OMe-rG
  • 2'- 0 -Methylguanosine
  • 2'-O-Methylguanosine
  • 2 '- Methoxyguanosine
  • Apoptosis,2’ OMe Guanosine,rRNA,inhibit,2’OMeGuanosine,Inhibitor,Nucleoside Antimetabolite/Analog,tRNA
  • 2’-O-Methylguanosine,RNA modified nucleoside Gm
  • 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one
  • 2'-O-Methylguanosine USP/EP/BP
  • 2'-OMe-rG
  • Guanosine, 2'-O-methyl-
  • 2'-O-MethylguanosineHydrate&gt
  • 2'-OMe-Gr
  • 2'-O-Methylguanosine Hydrate
  • 2-aMino-9-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-6,9-dihydro-1H-purin-6-one
  • 2'-O-Methyl Guanosine, >=99%
  • 2'-O-Methyl-D-guanosine
  • 2'-OMe Guanosine
  • 2-azanyl-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]-3H-purin-6-one
  • 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one
  • 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]-3H-purin-6-one
  • 2'-OMe-G

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