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2-THIOADENOSINE

2-THIOADENOSINE Structure
2-THIOADENOSINE
  • CAS No.43157-50-2
  • Chemical Name:2-THIOADENOSINE
  • CBNumber:CB2267322
  • Molecular Formula:C10H13N5O4S
  • Formula Weight:299.31
  • MOL File:43157-50-2.mol
2-THIOADENOSINE Property
  • Melting point >178°C (dec.)
  • Boiling point 544.5±60.0 °C(Predicted)
  • Density 2.18±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C(protect from light)
  • solubility Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
  • form Solid
  • pka 8.37±0.40(Predicted)
  • color Pale Yellow to Yellow
  • CAS DataBase Reference 43157-50-2
Safety
  • HS Code  :2934999090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

2-THIOADENOSINE Chemical Properties,Usage,Production

  • Description 2-Thioadenosine is a pharmaceutical intermediate compound used in the preparation of cangrelor, a P2Y12 platelet receptor antagonist used to prevent or reduce the risk of thrombosis during stenting procedures. In biology, it regulates the synthesis and degradation of important biomolecules such as DNA, RNA and proteins. It also regulates cell signalling pathways, including those involved in cell growth, proliferation and apoptosis. In addition, it plays a role in maintaining cellular redox balance and regulating oxidative stress.
  • Uses 2-Thioadenosine has application for developing platelet aggregation inhibitors.
  • Application Intermediate in the synthesis of cangrelor
2-THIOADENOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-THIOADENOSINE Spectrum
43157-50-2, 2-THIOADENOSINERelated Search:
  • 坎格雷洛中间体
  • 抑制剂
  • 中间体产品
  • 修饰性核苷
  • 医药中间体
  • 核苷
  • 化合物 2-MERCAPTOADENOSINE
  • 尖牙杂质6
  • 坎格雷洛杂质6
  • 腺苷杂质17
  • 2-硫腺苷
  • 坎格雷洛中间体1/2-巯基腺苷/腺苷-2-硫酮
  • 坎格雷洛中间体I
  • 6-氨基-9-((2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-3,9-二氢-2H-嘌呤-2-硫酮
  • 腺苷-2-硫酮
  • 2-硫代腺苷
  • 腺苷-2-硫酮 坎格雷洛中间体
  • 坎格雷洛中间体1
  • 腺苷-2-硫酮 坎格雷洛中间体 1KG
  • 2-硫代腺苷酸
  • 坎格瑞洛中间体
  • 43157-50-2
  • 6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purine-2-thione
  • Adenosine, 2,3-dihydro-2-thioxo-
  • 2-Thio-Ar
  • Adenosine Impurity 4
  • 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purine-2-thione
  • 2-Thioadenosine (Cangrelor intermediate 1)
  • 2-THIOADENOSINE
  • 2,3-dihydro-2-thioxoAdenosine
  • 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purine-2-thione
  • Cangrelor Impurity 6
  • Adenosine,1,2-dihydro-2-thioxo-
  • (2R,3R,4S,5R)-2-(6-aMino-2-Mercapto-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol