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15(R)-PROSTAGLANDIN E1

15(R)-PROSTAGLANDIN E1 Structure
15(R)-PROSTAGLANDIN E1
  • CAS No.19313-28-1
  • Chemical Name:15(R)-PROSTAGLANDIN E1
  • CBNumber:CB2233138
  • Molecular Formula:C20H36O5
  • Formula Weight:356.5
  • MOL File:19313-28-1.mol
15(R)-PROSTAGLANDIN E1 Property
  • Boiling point 541.4±35.0 °C(Predicted)
  • Density 1.075±0.06 g/cm3(Predicted)
  • storage temp. Refrigerator, under inert atmosphere
  • solubility Ethyl Acetate, Methanol, Tetrahydrofuran
  • form Colorless to pale yellow oil
  • pka 4.77±0.10(Predicted)
  • Stability Volatile
  • FDA UNII C1R6440YGW
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H319-H336
  • Precautionary statements P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

15(R)-PROSTAGLANDIN E1 Chemical Properties,Usage,Production

  • Description 13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.
  • Uses Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and can inhibit aggregation, ATP release, and thromboxane generation by human platelets. Prostaglandin E0 can also decrease the formation of cyclooxygenase (COX) metabolites by inhibiting the induction of COX-2 protein by LPS.
  • Definition ChEBI: 13,14-Dihydro PGE1 is a prostanoid.
15(R)-PROSTAGLANDIN E1 Preparation Products And Raw materials
Raw materials
Preparation Products
15(R)-PROSTAGLANDIN E1 Suppliers
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15(R)-PROSTAGLANDIN E1 Spectrum
19313-28-1, 15(R)-PROSTAGLANDIN E1Related Search:
  • 抑制剂
  • 13,14-DIHYDROPROSTAGLANDIN E1,PROSTAGLANDIN E1 (PGE1) METABOLITE
  • 前列地尔(前列腺素E1)杂质5(PGE0)
  • PROSTAGLANDIN E0 &GT;90% (20% SOLUTION IN ETHYL ACETATE)
  • 13,14-二氢前列腺素E1
  • 19313-28-1
  • 13,14-Dihydroprostaglandin E1, Prostaglandin E1 (PGE1) metabolite
  • Alprostadil (prostaglandin E1) Impurity 12 (PGE0)
  • Alprostadil (Prostaglandin E1) Impurity 5 (PGE0)
  • AlprostadilImpurity5
  • Prostaglandin E0 >90% (20% solution in ethyl acetate)
  • Prostaglandin E1 Impurity 5 (PGE0)
  • Prostan-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,15S)-
  • 90% (20% solution in ethyl acetate)
  • Prostaglandin E0 &gt
  • 9-oxo-11α,15S-dihydroxy-prostan-1-oic acid
  • Prostan-1-oic acid,11,15-dihydroxy-9-oxo-, (11a,15S)-
  • 13,14-Dihydro-prostaglandin E1 (PGE0)
  • (11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid
  • 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid
  • 13,14-dihydro PGE1
  • 13,14-Dihydroprostaglandinee1
  • PGE0
  • 13,14-DIHYDROPROSTAGLANDIN E1
  • 9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID

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