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DELTA12-PROSTAGLANDIN J2

DELTA12-PROSTAGLANDIN J2 Structure
DELTA12-PROSTAGLANDIN J2
  • CAS No.87893-54-7
  • Chemical Name:DELTA12-PROSTAGLANDIN J2
  • CBNumber:CB0706050
  • Molecular Formula:C20H30O4
  • Formula Weight:334.45
  • MOL File:87893-54-7.mol
DELTA12-PROSTAGLANDIN J2 Property
  • Boiling point 531.2±50.0 °C(Predicted)
  • Density 1.111±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12,
  • form Liquid
  • pka 4.75±0.10(Predicted)
  • color Colorless to light yellow
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H319-H336
  • Precautionary statements P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

DELTA12-PROSTAGLANDIN J2 Chemical Properties,Usage,Production

  • Description Δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 μg/ml. Δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand.
  • Uses Δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 μg/ml. Δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand.
  • Uses delta12-PGJ2 (delta12-Prostaglandin J2) is a decomposition product of PGD2 showing potent antiviral and anti-proliferative activity.
  • Definition ChEBI: 13,14-dihydro-Delta(12)-prostaglandin J2 is a member of the class of prostaglandins J that is prosta-5,9,12-trien-1-oic acid carrying oxo and hydsroxy substituents at positions 11 and 15 respectively (the 5Z,12E,15S-stereoisomer). It has a role as an antineoplastic agent and an antiviral agent. It is a prostaglandins J and a secondary alcohol. It is functionally related to a prostaglandin J2. It is a conjugate acid of a 13,14-dihydro-Delta(12)-prostaglandin J2(1-).
  • IC 50 Human Endogenous Metabolite
DELTA12-PROSTAGLANDIN J2 Preparation Products And Raw materials
Raw materials
Preparation Products
DELTA12-PROSTAGLANDIN J2 Suppliers
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DELTA12-PROSTAGLANDIN J2 Spectrum
87893-54-7, DELTA12-PROSTAGLANDIN J2Related Search:
  • 抑制剂
  • 生化试剂
  • 中药对照品
  • C20H30O4
  • 拉坦前列腺素杂质25
  • 化合物 DELTA-12-PROSTAGLANDIN J2
  • Δ12-前列腺素J2
  • 87893-54-7
  • Δ12-PGJ2 (Δ12-Prostaglandin J2)
  • Δ12-Prostaglandin J2
  • Prosta-5,9,12-trien-1-oic acid, 15-hydroxy-11-oxo-, (5Z,12E,15S)-
  • Delta12-PGJ2 (Delta12-Prostaglandin J2)
  • TUXFWOHFPFBNEJ-GJGHEGAFSA-N
  • 13,14-dihydro-Delta(12)-prostaglandin J2
  • Δ12-PGJ2 (Δ12-Prostaglandin J2)
  • Δ12-Prostaglandin J2 Lipid Maps MS Standard
  • 11-OXO-15S-HYDROXY-PROSTA-5Z,9,12E-TRIEN-1-OIC ACID
  • 12-PROSTAGLANDIN J2
  • DELTA12-PGJ2
  • DELTA12-PROSTAGLANDIN J2
  • C05958
  • Δ12-PGJ2
  • (5Z,12E,15S)-15-Hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid
  • (5Z,12E,15S)-11-Oxo-15-hydroxyprosta-5,9,12-triene-1-oic acid
  • 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2
  • (Z)-7-[(1S,5E)-5-[(3S)-3-hydroxyoctylidene]-4-oxo-1-cyclopent-2-enyl]hept-5-enoic acid

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