ChemicalBook > CAS DataBase List > Vanillylidenacetone

Vanillylidenacetone

CAS No.1080-12-2
Chemical Name:Vanillylidenacetone
CBNumber:CB2126546
Molecular Formula:C11H12O3
Formula Weight:192.21
MOL File:1080-12-2.mol

Vanillylidenacetone Property

Melting point 125-130 °C
Boiling point 268.19°C (rough estimate)
Density 1.1503 (rough estimate)
refractive index 1.4600 (estimate)
FEMA 3738 | VANILLYLIDENE ACETONE
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form solid
pka 9.94±0.31(Predicted)
color Pale yellow
Odor at 100.00 %. sweet powdery vanilla creamy balsam
Odor Type vanilla
JECFA Number 732
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
LogP 1.40
CAS DataBase Reference 1080-12-2(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) VANILLYLIDENE ACETONE
EWG's Food Scores 1
FDA UNII 8CJX5I27B7
EPA Substance Registry System 3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)- (1080-12-2)
UNSPSC Code 12352200
NACRES NA.22

Safety

Risk Statements :36/37/38
Safety Statements :26-36/37/39
WGK Germany :3
RTECS :EM9960000
F :10-23
HS Code :29145090
Toxicity :LD50 intraperitoneal in mouse: 610mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H315-H319-H335
Precautionary statements P261-P305+P351+P338

Vanillylidenacetone Price More Price(2)

Brand: Sigma-Aldrich(India)
Product number: 90609
Product name : Vanillylidenacetone
Purity: analytical standard
Packaging: 100MG
Price: ₹6603.25
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 07551
Product name : Vanillylidenacetone
Purity: ≥98.5%
Packaging: 5G
Price: ₹10392
Updated: 2022/06/14
Buy: Buy

Vanillylidenacetone Chemical Properties,Usage,Production

Description Dehydrozingerone (1080-12-2) is a structural half analog of curcumin (Cat.# 10-1243) and is isolated from ginger rhizomes. Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been shown to possess various antitumor effects2,3 and inhibit growth factor/peroxide-stimulated vascular smooth muscle function4.
Chemical Properties Vanillylidene acetone has a very sweet, warm and tenacious odor.
Physical properties Yellowish, needlelike crystals. Slightly soluble in water, soluble in alcohol and oils.
Uses Vanillylidenacetone is one of ferulic acid derivatives. Studies have shown that vanillyl acetone has a certain inhibitory effect on Amaranthus, barnyardgrass, matang, dogwood and rape, among which the best inhibitory effect is on rape and Amaranthus.
Definition ChEBI: Dehydrozingerone is a hydroxycinnamic acid.
Taste threshold values Taste characteristics at 200 ppm: balsamic vanilla, with sweet aromatic spicy nuances.
References 1) Kubra et al. (2014), Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds; J. Food Sci. Technol., 51 245 2) Motohashi et al. (1998), Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation; Cancer Lett., 134 37 3) Yogosawa et al. (2012), Dehydrozingerone, a structural analog of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells; J. Nat. Prod., 75 2088 4) Liu et al. (2008), Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function; J. Cardiovasc. Pharmacol., 52 422