ChemicalBook > CAS DataBase List > HOMOBUTEIN

HOMOBUTEIN

HOMOBUTEIN Structure
HOMOBUTEIN
  • CAS No.34000-39-0
  • Chemical Name:HOMOBUTEIN
  • CBNumber:CB0382919
  • Molecular Formula:C16H14O5
  • Formula Weight:286.28
  • MOL File:34000-39-0.mol
HOMOBUTEIN Property
  • Melting point 207-212°C
  • Boiling point 523.8±50.0 °C(Predicted)
  • Density 1.369±0.06 g/cm3(Predicted)
  • pka 7.43±0.35(Predicted)
  • form Solid
  • color Light yellow to yellow
  • LogP 2.880 (est)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

HOMOBUTEIN Chemical Properties,Usage,Production

  • Uses Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation[1][2][3][4].
  • Definition ChEBI: Homobutein is a member of chalcones.
  • IC 50 Toxoplasma
  • References [1] Orlikova B, et al. Natural chalcones as dual inhibitors of HDACs and NF-κB. Oncol Rep. 2012 Sep;28(3):797-805. DOI:10.3892/or.2012.1870
    [2] Adeyemi OS, et al. In Vitro Screening to Identify Anti-Toxoplasma Compounds and In Silico Modeling for Bioactivities and Toxicity. Yale J Biol Med. 2019 Sep 20;92(3):369-383. PMID:31543702
    [3] Yenesew A, et al. Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica. Phytochemistry. 2004 Nov;65(22):3029-32. DOI:10.1016/j.phytochem.2004.08.050
    [4] Serobatse K, et al. Antioxidant and antimalarial properties of butein and homobutein based on their ability to chelate iron (II and III) cations: a DFT study in vacuo and in solution. European Food Research and Technology, 2016, 242(1): 71-90.
HOMOBUTEIN Preparation Products And Raw materials
Raw materials
Preparation Products
HOMOBUTEIN Suppliers
Global(57)Suppliers
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29858
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：
  • Email：support@targetmol.com
  • Country：United States
  • ProdList：38630
  • Advantage：58
  • Supplier：
    Henan Fengda Chemical Co., Ltd
  • Tel：+86-371-86557731<br/>+86-13613820652
  • Email：info@fdachem.com
  • Country：China
  • ProdList：20235
  • Advantage：58
  • Supplier：
    Chongqing Chemdad Co., Ltd
  • Tel：+86-023-6139-8061<br/>+86-86-13650506873
  • Email：sales@chemdad.com
  • Country：China
  • ProdList：39927
  • Advantage：58
HOMOBUTEIN Spectrum
34000-39-0, HOMOBUTEINRelated Search:
  • Chalcones
  • 查耳酮
  • 抑制剂
  • 标准品
  • 植物提取物
  • 同羟基丁胺
  • 高紫柳查尔酮/生物碱类(ALKALOIDS)
  • 化合物HOMOBUTEIN
  • 高紫柳查尔酮
  • 34000-39-0
  • homobitein
  • 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
  • 3-METHOXY-2',4',4-TRIHYDROXYCHALCONE
  • 2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE
  • Einecs 251-782-7
  • 4,2',4'-Trihydroxy-3-methoxychalcone
  • (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one
  • HOMOBUTEIN hplc
  • HOMOBUTEIN WITH HPLC
  • 3-O-methylbutein
  • (E)-2',4,4'-trihydroxy-3-methoxychalcone
  • HOMOBUTEIN

Home

My