ChemicalBook > CAS DataBase List > Butyl chloroformate
Butyl chloroformate
Butyl chloroformate
- CAS No.592-34-7
- Chemical Name:Butyl chloroformate
- CBNumber:CB1692042
- Molecular Formula:C5H9ClO2
- Formula Weight:136.58
- MOL File:592-34-7.mol
Butyl chloroformate Property
- Melting point -70 °C
- Boiling point 142 °C(lit.)
- Density 1.074 g/mL at 25 °C(lit.)
- vapor pressure 2.42 psi ( 20 °C)
- refractive index n
20/D 1.412(lit.) - Flash point 77 °F
- storage temp. 2-8°C
- form Liquid
- color Clear
- Water Solubility DECOMPOSES
- Sensitive Moisture Sensitive
- BRN 605635
- LogP 1.895 (est)
- CAS DataBase Reference 592-34-7(CAS DataBase Reference)
- EWG's Food Scores 1
- FDA UNII 3TGX130CB0
- NIST Chemistry Reference Carbonochloridic acid, butyl ester(592-34-7)
- EPA Substance Registry System n-Butyl chloroformate (592-34-7)
Safety
-
Symbol(GHS)
- Signal wordDanger
- Hazard statements H226-H314-H331
- Precautionary statements P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Butyl chloroformate Chemical Properties,Usage,Production
- Chemical Properties clear liquid
- Uses Butyl Chloroformate is a reactant in the preparation of Lapatinib derivatives as HER1/HER2 targeting antitumor drugs.
- General Description A colorless liquid. Flash point near 70°F. Very toxic by inhalation. Denser than water. Used to make other chemicals.
- Air & Water Reactions Highly flammable. Decomposes exothermically in water to give hydrochloric acid and organic acids.
- Reactivity Profile Butyl chloroformate is incompatible with bases (including amines), with water, with strong oxidizing agents, with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
- Health Hazard Inhalation of vapor irritates nose and throat and can cause delayed pulmonary edema. Liquid irritates eyes and causes severe skin burns and irreversible skin damage if allowed to remain. Can cause blindness. Ingestion causes burns of mouth and stomach.
- Flammability and Explosibility Flammable
Butyl chloroformate Preparation Products And Raw materials
Raw materials
Preparation Products
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- ClCOOC4H9
- ClCOOCH2CH2CH2CH3
- ClCO2CH2CH2CH2CH3
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- 592-34-7
- butyl carbonochloridate
- BUTYL CHLOROFORMATE (CAS NO.592-34-7)
- Butyl Chloroformate >
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