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CUCURBITACIN D

CUCURBITACIN D Structure
CUCURBITACIN D
  • CAS No.3877-86-9
  • Chemical Name:CUCURBITACIN D
  • CBNumber:CB1119385
  • Molecular Formula:C30H44O7
  • Formula Weight:516.67
  • MOL File:3877-86-9.mol
CUCURBITACIN D Property
  • Melting point 151.5°C
  • Boiling point 521.47°C (rough estimate)
  • Density 1.0814 (rough estimate)
  • refractive index 1.5820 (estimate)
  • storage temp. 4°C, protect from light
  • solubility Soluble in ethanol and methan
  • form powder
  • pka 12.66±0.29(Predicted)
  • color White
  • LogP 1.480 (est)
  • CAS DataBase Reference 3877-86-9
  • FDA UNII 5I62H4ORC7
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • Hazard Codes  :Xi
  • HS Code  :29144000
  • Toxicity :LD50 oral in rat: 8200ug/kg
  • NFPA 704:
    0
    4 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300
  • Precautionary statements P301+P310+P330

CUCURBITACIN D Chemical Properties,Usage,Production

  • Uses Cucurbitacin D acts as a potential potent anti-cancer agent in various cervical cancers through induction of apopotosis.
  • Definition ChEBI: A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23.
  • in vivo

    Cucurbitacin D (1 mg/kg, intratumoral injection, three times a week for four weeks) inhibits tumor proliferation in mice[3].

    Animal Model:Xenograft cervical cancer cell model in nude mice[3]
    Dosage:1 mg/kg; three times a week; four weeks
    Administration:Intratumoral injection
    Result:Reduced tumor volume and weight, and the expression of pAKT and pSTAT3 proteins was significantly reduced.
  • IC 50 HSP90
CUCURBITACIN D Preparation Products And Raw materials
Raw materials
Preparation Products
CUCURBITACIN D Suppliers
Global(163)Suppliers
  • Supplier：
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    BOC Sciences
  • Tel：+1-631-485-4226
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  • Supplier：
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  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
CUCURBITACIN D Spectrum
3877-86-9, CUCURBITACIN DRelated Search:
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  • 萜类
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  • (2S,8S,9R,10R,13R,14S,16R,17R)-17-((R,E)-2,6-二羟基-6-甲基-3-氧代庚-4-烯-2-基)-2,16-二羟基-4,4,9,13,14-五甲基-1,4,7,8,9,12,13,15,16,17-十二氢-3H-环戊[A]菲-3,11(2H)-二酮
  • 葫芦素D/萜类
  • 葫芦素D标准品
  • 葫芦素D对照品
  • 葫芦素D(甄准不供应)
  • CUCURBITACIN D 葫芦素D
  • 葫芦素D(葫芦苦素D)
  • 葫芦苦素D
  • 葫芦素 D
  • 3877-86-9
  • Cucurbitacin D-RM
  • CUCURBITACIN D(AS) 10mg
  • 19-Norlanosta-5,23-diene-3,11,22-trione, 2,16,20,25-tetrahydroxy-9-methyl-, (2β,9β,10α,16α,23E)-
  • Cucurbit D
  • 17-[(3E)-1,5-Dihydroxy-1,5-dimethyl-2-oxohex-3-en-1-yl]-2,16-dihydroxy-4,4,9,14-tetramethylestr-5-ene-3,11-dione
  • (9β,10α,23E)-2β,16α,20,25-Tetrahydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione
  • (10α,23E)-2β,16α,20,25-Tetrahydroxy-9β-methyl-19-norlanosta-5,23-diene-3,11,22-trione
  • CUCURBITACIN D WITH HPLC
  • elatericinea
  • cucurbitacine(d)
  • 20,25-tetrahydroxy-ph
  • ELATERICIN A
  • CUCURBITACIN D

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