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propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Structure
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
  • CAS No.1421-14-3
  • Chemical Name:propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
  • CBNumber:CB0875008
  • Molecular Formula:C18H27NO5
  • Formula Weight:337.41
  • MOL File:1421-14-3.mol
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Property
  • Boiling point bp0.7 210-212°
  • Density 1.2043 (rough estimate)
  • refractive index 1.5000 (estimate)
  • storage temp. Refrigerator
  • solubility DMSO (Slightly), Ethyl Acetate (Slightly)
  • form Oil
  • color Pale Yellow to Yellow
  • FDA UNII AO82L471NS
  • ATC code N01AX04
  • EPA Substance Registry System Propanidid (1421-14-3)
Safety
  • Toxicity :LD50 orally in rats: >10,000 mg/kg (Goldenthal)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Chemical Properties,Usage,Production

  • Chemical Properties yellow oil bp0.7 210-212°C soluble in alcohol, chloroform, essentially water insoluble anasthetic Epontol (Bayer) Sombrevin
  • Uses Sombrevin, is an ultra short-acting phenylacetate general anesthetic.
  • Uses Anesthetic (intravenous).
  • Definition ChEBI: Propanidid is a member of methoxybenzenes.
  • brand name Epontol (Farbenfabriken Bayer A.G., Germany).
  • Clinical Use Propanidid is used as a very short- to shortacting intravenous anesthetic for minor surgery and gynecology. It is characterized by rapid onset of and quick recovery from anesthesia, producing surgical anesthesia for 3 – 4 min. Repeated injections can be used to prolong the anesthesia. Postanesthetic sleep does not occur because the propyl ester is hydrolyzed rapidly in the patient to form inactive 3-methoxy-4- (N,N-diethylcarbamoylmethoxy)phenylacetic acid. After 20 – 30 min the patients generally are completely responsive .
  • Synthesis Propanidid , propyl 3- methoxy-4-(N,N-diethylcarbamoylmethoxy)- phenylacetate, is a colorless to pale yellowish water-insoluble oil. It is prepared from the propyl ester of sodium homovanillic acid and N,N-diethylchloroacetamide .
    Synthesis_1421-14-3
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Preparation Products And Raw materials
Raw materials
Preparation Products
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Suppliers
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propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Spectrum
1421-14-3, propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetateRelated Search:
  • 抑制剂
  • 化合物 T34146
  • 普尔安
  • 丙酯胺苯二醚
  • 丙泮尼地
  • 1421-14-3
  • propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate/Sombrevin
  • BAY-1420, Sombrevin
  • Fabontal
  • Fabantol
  • BAY-1420
  • propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate USP/EP/BP
  • Benzeneacetic acid, 4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-, propyl ester
  • KEJXLQUPYHWCNM-UHFFFAOYSA-N
  • propyl 2-[4-[2-(diethylamino)-2-oxo-ethoxy]-3-methoxy-phenyl]ethanoate
  • propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate
  • 2-[4-[2-(diethylamino)-2-keto-ethoxy]-3-methoxy-phenyl]acetic acid propyl ester
  • WH-5668
  • TH-2180
  • Sombrevin
  • FBA-1420
  • Epontol
  • Bayer-1420
  • PROPANIDIDE
  • propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
  • propanidid

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