1421-14-3

yellow oil bp0.7 210-212°C soluble in alcohol, chloroform, essentially water insoluble anasthetic Epontol (Bayer) Sombrevin

Anesthetic (intravenous).

Sombrevin, is an ultra short-acting phenylacetate general anesthetic.

ChEBI: Propanidid is a member of methoxybenzenes.

Epontol (Farbenfabriken Bayer A.G., Germany).

Propanidid is used as a very short- to shortacting intravenous anesthetic for minor surgery and gynecology. It is characterized by rapid onset of and quick recovery from anesthesia, producing surgical anesthesia for 3 – 4 min. Repeated injections can be used to prolong the anesthesia. Postanesthetic sleep does not occur because the propyl ester is hydrolyzed rapidly in the patient to form inactive 3-methoxy-4- (N,N-diethylcarbamoylmethoxy)phenylacetic acid. After 20 – 30 min the patients generally are completely responsive .

Propanidid , propyl 3- methoxy-4-(N,N-diethylcarbamoylmethoxy)- phenylacetate, is a colorless to pale yellowish water-insoluble oil. It is prepared from the propyl ester of sodium homovanillic acid and N,N-diethylchloroacetamide .