Chemical Properties
white to beige powder
Uses
It reacts with formaldehyde in the presence of acid to give an isochromanone.
Uses
Homoveratric Acid is a dopamine metabolite that inhibits brain mitochondrial respiration via monoamine oxidase/H2O2-dependent or non-dependent pathway.
Definition
ChEBI: Homoveratric acid is a phenylacetic acid substituted at positions 3 and 4 by methoxy groups. It has a role as a human urinary metabolite and a human xenobiotic metabolite. It is a dimethoxybenzene and a member of phenylacetic acids.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 2, p. 333, 1943
The Journal of Organic Chemistry, 15, p. 548, 1950
DOI: 10.1021/jo01149a016
Purification Methods
Crystallise homoveratric acid from H2O or *C6H6/ligroin. The amide has m 142o (from H2O). [Beilstein 10 H 409, 10 I 197, 10 II 268, 10 III 1459, 10 IV 1509.]
