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ARTEMISININ
ARTEMISININ
- CAS No.491-54-3
- Chemical Name:ARTEMISININ
- CBNumber:CB0387974
- Molecular Formula:C16H12O6
- Formula Weight:300.26
- MOL File:491-54-3.mol
ARTEMISININ Property
- Melting point 156-157 °C(lit.)
- Boiling point 543.8±50.0 °C(Predicted)
- Density 1.538
- storage temp. Keep in dark place,Inert atmosphere,2-8°C
- solubility Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat
- pka 6.32±0.40(Predicted)
- form Solid
- color Yellow
- BRN 305378
- LogP 2.740 (est)
- CAS DataBase Reference 491-54-3
- FDA UNII 508XL61MPD
- UNSPSC Code 85151701
- NACRES NA.24
Safety
- Safety Statements :24/25
- WGK Germany :2
- RTECS :KD4170000
- HS Code :29329990
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
ARTEMISININ Price
More Price(3)
- Brand: Sigma-Aldrich(India)
- Product number: 69545
- Product name : Kaempferide
- Purity: analytical standard
- Packaging: 10MG
- Price: ₹40821.08
- Updated: 2022/06/14
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: K0057
- Product name : Kaempferide
- Purity: min. 96.0 %
- Packaging: 10MG
- Price: ₹5500
- Updated: 2022/05/26
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: K0057
- Product name : Kaempferide
- Purity: min. 96.0 %
- Packaging: 50MG
- Price: ₹13000
- Updated: 2022/05/26
- Buy: Buy
ARTEMISININ Chemical Properties,Usage,Production
- Chemical Properties Yellow powder
- Uses Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumour possibilities. Impurity of Icaritin (I163700).
- Definition ChEBI: A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol.
- Biological Activity the effects of phytoestrogens have been studied in the hypothalamic-pituitary-gonadal axis and various non-gonadal targets. epidemiologic and experimental evidence indicates a protective effect of phytoestrogens also in colorectal cancer. the mechanism through which estrogenic molecules control colorectal cancer tumorigenesis could possibly involve estrogen receptor β, which is the predominantly expressed estrogen receptor subtype in colon mucosa.
- in vitro kaempferide triglycoside proved to inhibit the proliferation of native and estrogen receptor β overexpressing colon cancer cells via a mechanism not mediated by ligand binding dependent estrogen receptor activation. it affected hct8 cell cycle progression through increasing the g0/g1 cell fraction and in estrogen receptor β overexpressing cells increased two antioxidant enzymes [1].
- in vivo the aim of one previous study was to evaluate the effect of kaempferol on tissue lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal cancer in male wistar rats and to compare its efficacy with irinotecan. this study revealed that kaempferol could be safely used as a chemopreventive agent in colorectal cancer [2].
-
References
[1] martineti v, tognarini i, azzari c, carbonell sala s, clematis f, dolci m, lanzotti v, tonelli f, brandi ml, curir p. inhibition of in vitro growth and arrest in the g0/g1 phase of hct8 line human colon cancer cells by kaempferide triglycoside from dianthus caryophyllus. phytother res. 2010 sep;24(9):1302-8.
[2] nirmala p, ramanathan m. effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. eur j pharmacol. 2011 mar 1;654(1):75-9.
ARTEMISININ Preparation Products And Raw materials
Raw materials
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491-54-3, ARTEMISININRelated Search:
- Kaempferol Ginkgo biloba extract FructussSophoraeExtract KAEMPFERITRIN KAEMPFEROL-3-O-RUTINOSIDE KAEMPFEROL-7-O-GLUCOSIDE Kaempferol 3-neohesperidoside Kaempferol 3-(6-O-glucopyranosylglucoside) Kaempferol 3-sophoroside-7-glucoside kaempferol 3-O-sophoroside KaeMpferol 3-sophoroside-7-rhaMnoside KAEMPFEROL 3-A-L-ARABINOPYRANOSIDE 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE CASTICIN Icariin TAMARIXETIN Arteannuin, Qinghaosu,Artemisine,Artemisinin,Arteannuin,ARTEANNUIN,(+)-Arteannuin,Arteannuin99% arteannuin B
- standardized herbal extract
- reference standards from Chinese medicinal herbs (TCM).
- phytochemical
- pharmaceutical intermediate
- chemical reagent
- Flavanols
- 中药标准品,对照品
- 抑制剂
- 国家标准物质
- 高端化学
- 原料药
- 试剂
- 标准品,对照品
- 标准品 -中药标准品
- 黄酮
- 标准品-中药标准品
- 分析试剂标准品
- 对照品
- 植物提取物
- 高纯试剂
- 分析标准品
- 标准品
- 中药对照品
- 植提标准品
- 中药标准品
- 山奈素,10 MM DMSO 溶液
- 山柰素(山柰酚-4'-O-甲醚)
- 山奈素/GC
- 甲醇中山奈素
- 甲醇中山奈素溶液标准物质
- KAEMPFEROL 4'-O-METHYL ETHER|||山奈素|||KAEMPFEROL 4'-METHYL ETHER|||4'-METHYLKAEMPFEROL|||4'-O-METHYLKAEMPFEROL
- 山奈素对照品
- 标准品对照品】KAEMPFERIDE
- 山柰酚-4'-O-甲醚
- 山柰素 ( 山柰酚-4'-甲醚)
- 淫羊藿素杂质1
- 山柰素-4'-甲醚
- 山柰酚-4-O-甲醚 491-54-3
- 3,5,7-三羟基-2-(4-甲氧基苯基)-4H-苯并吡喃-4-酮
- 山奈素杂质
- 山奈素(山柰素)
- 山柰甲黄素
- KAEMPFERIDE 山奈素
- 山奈素(,山奈酚-4'-O-甲醚)
- 山奈酚-4'-O-甲醚
- 3,5,7-三羟基-4'-甲氧基黄酮
- 山奈素, 来源于山奈
- 莰非素
- 山奈素
- 山奈素(标准品)
- 3,5,7-三羟基-2-(4-甲氧基苯基)-4H-1-苯并吡喃-4-酮
- 491-54-3
- kaempferide, 10 mM in DMSO
- Kaempferide-RM
- 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-alpha-L-mannopyranoside
- Kaempferol 4'-O-methyl ether|||Kaempferol 4'-methyl ether|||4'-Methylkaempferol|||4'-O-Methylkaempferol
- Icaritin Impurity 1
- kaempferid