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Tiapride hydrochloride

Tiapride hydrochloride Property

Melting point approximate 200℃ (dec.)
storage temp. 2-8°C
solubility Very soluble in water, soluble in methanol, slightly soluble in anhydrous ethanol.
form Solid
color White
Merck 14,9421
CAS DataBase Reference 51012-33-0(CAS DataBase Reference)
FDA UNII 25N106WEDO
UNSPSC Code 41116107
NACRES NA.24

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Tiapride hydrochloride Chemical Properties,Usage,Production

Chemical Properties White Solid
Originator Tiapridal,Delagrange,France,1977
Uses Tiapride is a D2 and D3 dopamine receptor antagonist and a antipsychotic drug predominately used in the pharmacotherapy of patients with dementia.
Uses Dopamine antagonist;Antidyskinetic
Uses Tiapride hydrochloride is a D2 and D3 dopamine receptor antagonist and a antipsychotic drug predominately used in the pharmacotherapy of patients with dementia.
Definition ChEBI: Tiapride hydrochloride is a member of benzamides.
Manufacturing Process 5 g of 2-methoxy-5-methylsulfonylbenzoic acid, 50 ml of dioxan, 3.02 ml of triethylamine and 3 g of isobutyl chloroformate were introduced into a 250 ml balloon flask at ambient temperature.
After the mixture had been stirred for 30 minutes, 3 g of N,N_x0002_diethylethylenediamine were added. The reaction mixture was stirred for 6 hours and the solvents were evaporated under vacuum.
The residue was dissolved in 50 ml of water and the solution was made alkaline with sodium hydroxide. The precipitate formed was filtered, washed and dried in a drying oven at 60°C. 6 g of N-(diethylaminoethyl)-2-methoxy- 5-methylsulfonylbenzamide (melting point: 124°C to 125°C) was produced.
Therapeutic Function Antiemetic

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Tiapride hydrochloride Spectrum

51012-33-0, Tiapride hydrochlorideRelated Search:

抑制剂
生化试剂
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有机中间体
医药原料
小分子抑制剂
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C15H24N2O4SClH
51012-32-0
盐酸噻必利
盐酸硫必利 EP标准品
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N-[2-(二乙基氨基)乙基]-2-甲氧基-5-(甲基磺酰基)苯甲酰胺盐酸盐
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51012-33-0
Tiapride HCl - Bio-X ?
Urea USP Related Compound A
Tiapride HCl (Tiapridal)
Tiapride hydrochloride USP/EP/BP
Tiapride hydrochloride CRS
TIAPRIDE HYDROCHLORIDE
Tiaryl
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Tiapridhydrochlorid
TiapridHCl
N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulphonyl)benzamide monohydrochloride
n-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)-benzamidmonohydrochloride
n-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)-benzamidmonohydroch
n-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamidehydrochloride
N-[2-(DIETHYLAMINO)ETHYL]-5-[METHYL-SULFONYL]-O-ANISAMIDE HYDROCHLORIDE