ChemicalBook > CAS DataBase List > Tiapride
Tiapride
Tiapride
- CAS No.51012-32-9
- Chemical Name:Tiapride
- CBNumber:CB0213532
- Molecular Formula:C15H24N2O4S
- Formula Weight:328.43
- MOL File:51012-32-9.mol
Tiapride Property
- Melting point 123-125°
- vapor pressure 0Pa at 25℃
- storage temp. 2-8°C
- pka 9.14[at 20 ℃]
- Water Solubility 349mg/L at 25℃
- LogP 0.9
- CAS DataBase Reference 51012-32-9(CAS DataBase Reference)
- FDA UNII LAH70H9JPH
- ATC code N05AL03
Safety
- WGK Germany :2
- RTECS :CV4203800
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Tiapride Chemical Properties,Usage,Production
- Originator Tiapridal,Delagrange,France,1977
- Uses diuretic, antihypertensive
- Uses Tiapride hydrochloride is a D2DR and D3DR inhibitor; Anti-psychotic agent and alternative treatment for Tourette’s syndrome.
- Definition ChEBI: N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide is a member of benzamides.
-
Manufacturing Process
5 g of 2-methoxy-5-methylsulfonylbenzoic acid, 50 ml of dioxan, 3.02 ml of
triethylamine and 3 g of isobutyl chloroformate were introduced into a 250 ml
balloon flask at ambient temperature.
After the mixture had been stirred for 30 minutes, 3 g of N,N_x0002_diethylethylenediamine were added. The reaction mixture was stirred for 6 hours and the solvents were evaporated under vacuum.
The residue was dissolved in 50 ml of water and the solution was made alkaline with sodium hydroxide. The precipitate formed was filtered, washed and dried in a drying oven at 60°C. 6 g of N-(diethylaminoethyl)-2-methoxy- 5-methylsulfonylbenzamide (melting point: 124°C to 125°C) was produced. - brand name Tiapride Hydrochloride is JAN.
- Therapeutic Function Antiemetic
Tiapride Preparation Products And Raw materials
Raw materials
Preparation Products
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51012-32-9, TiaprideRelated Search:
- Chlorantraniliprole Ethyl acrylate p-Aminobenzamide Ethanol Benzamide ISOXADIFEN-ETHYL Ethyl propiolate Ethyl acetate Ethyl cyanoacetate Ethylparaben Trinexapac-ethyl TERT-BUTYL ISOCYANIDE Sultopride hydrochloride Benzyl isocyanide PHENYLSELENOL SALCOMINE TIAPRIDE HYDROCHLORIDE Tosylmethyl isocyanide
- Active Pharmaceutical Ingredients
- NATURETIN
- Dopamine receptor
- 抑制剂
- API原料药-兽药原料药
- 分析试剂-对照品
- 植物提取物
- 化合物 TIAPRIDE
- N-(2-(二乙氨基)乙基)-2-甲氧基-5-(甲磺酰基)苯甲酰胺
- 硫必利C
- 泰必利
- 黄杨木生物碱I
- 环锦热黄杨碱 D
- 黄杨碱
- N-[2-(二乙基氨基)乙基]-2-甲氧基-5-(甲基磺酰基)苯甲酰胺
- 泰必乐
- 硫必利
- 51012-32-9
- Tiapride Impurity
- Tiapride USP/EP/BP
- Benzamide, N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)-
- thiapride
- N-(Diethylaminoethyl)-2-methoxy-5-methylsulfonyl-benzamide
- n-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)-benzamid
- flo1347
- LABOTEST-BB LT00772311
- N-[2-(Diethylamino)ethyl]-2-methoxy-5-(methylsulphonyl)benzamide
- N-[2-(Diethylamino)ethyl]-5-mesyl-2-methoxybenzamide
- N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-2-methoxybenzamide
- N-[2-(Ethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide
- N-(2-Diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide
- Cyclovirobune D
- N-[2-Diethylamino ethyl]-5-[methylsufonyl]-o-anisamide
- Tiapride hcl
- TIAPRIDE