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2-Hydroxy-2-methylpropiophenone

Uses

CAS No.7473-98-5
Chemical Name:2-Hydroxy-2-methylpropiophenone
CBNumber:CB0150675
Molecular Formula:C10H12O2
Formula Weight:164.2
MOL File:7473-98-5.mol

2-Hydroxy-2-methylpropiophenone Property

Melting point 4°C
Boiling point 102-103 °C4 mm Hg(lit.)
Density 1.077 g/mL at 25 °C(lit.)
vapor pressure 0.57Pa at 20℃
refractive index n20/D 1.533(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Practically insoluble in water
form clear liquid
pka 13.23±0.29(Predicted)
Specific Gravity 1.077
color Colorless to Light orange to Yellow
Odor Slight odor
Water Solubility 13.3g/L at 20℃
InChIKey XMLYCEVDHLAQEL-UHFFFAOYSA-N
LogP 1.62 at 25℃
CAS DataBase Reference 7473-98-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII Z0LRG273AD
EPA Substance Registry System 1-Propanone, 2-hydroxy-2-methyl-1-phenyl- (7473-98-5)
UNSPSC Code 12162002
NACRES NA.23

Safety

Hazard Codes :Xn
Risk Statements :22
Safety Statements :23-36/37/39
RIDADR :3082
WGK Germany :3
RTECS :UC2977245
HazardClass :9
PackingGroup :III
HS Code :29144000

NFPA 704:

	1
0		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302
Precautionary statements P264-P270-P301+P312-P501

2-Hydroxy-2-methylpropiophenone Price More Price(8)

Brand: Sigma-Aldrich(India)
Product number: 405655
Product name : 2-Hydroxy-2-methylpropiophenone
Purity: 97%
Packaging: 50ML
Price: ₹6246.03
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 405655
Product name : 2-Hydroxy-2-methylpropiophenone
Purity: 97%
Packaging: 250ML
Price: ₹17417.43
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: H0991
Product name : 2-Hydroxy-2-methylpropiophenone
Purity: min. 96.0 %
Packaging: 25G
Price: ₹2800
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: H0991
Product name : 2-Hydroxy-2-methylpropiophenone
Purity: min. 96.0 %
Packaging: 100G
Price: ₹5500
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: H0991
Product name : 2-Hydroxy-2-methylpropiophenone
Purity: min. 96.0 %
Packaging: 500G
Price: ₹10700
Updated: 2022/05/26
Buy: Buy

2-Hydroxy-2-methylpropiophenone Chemical Properties,Usage,Production

Uses
2-Hydroxy-2-methylpropiophenone is a photoinitiator.In addition, 2-hydroxy-2-methylpropiophenone is an important organic intermediate (building block) to synthetize substituted propiophenone products.
Chemical Properties Yellowish clear liquid
Uses 2-Hydroxy-2-benzoylpropane was used as a catalyst in real-time kinetic study of laser-induced polymerization. It is also a photoinitiator.
Synthesis Reference(s) Tetrahedron Letters, 29, p. 4365, 1988 DOI: 10.1016/S0040-4039(00)80496-7
General Description 2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications.
Hazard Moderately toxic by ingestion.
Flammability and Explosibility Not classified
Synthesis KBr in water is added to a solution of 2-methyl-1-phenylpropane-1,2-diol in toluene. Then, TEMPO is added. The reddish suspension is cooled to 0°C. A 12 % sodium hypochlorite solution is added while maintaining the internal temperature at 5°C or lower. The mixture is stirred for 1 h at 0-5°C and then separated for 10 min. Sodium dithionite solution (obtained from 30 g sodium dithionite (85%) and 400 ml of water)is added to the organic phase and stirred at 85°C for 1-2 h. The organic phase is again separated and concentrated (rotavap). The crude product is then subjected to fractional distillation, yielding 2-Hydroxy-2-methylpropiophenone as a colorless oil.
Toxics Screening Level The ITSL for 2-hydroxy-2-methyl-1-phenyl-1-propanone has been changed from 0.04 μg/m3 to 0.1 μg/m3 based on annual averaging time.