The combination of Robinin and methotrexate (50 mg/kg and 0.3 mg/kg, Oral gavage, Twice a week) has anti-inflammatory and anti-arthritic action in adjuvant arthritis mice models[3].
Robinin (50 mg/kg, Oral gavage, 10 days) can modulate the cardioprotective effect of the TGF-β1 signaling pathway on Adriamycin-induced cardiotoxicity[4].
| Animal Model: | Adjuvant arthritis mice model[3] |
| Dosage: | 50 mg/kg Robinin and 0.3 mg/kg MTX twice a week |
| Administration: | Oral gavage (p.o.) |
| Result: | Had anti-inflammatory and anti-arthritic action. |
| Animal Model: | Sprague Dawley rats model[4] |
| Dosage: | 50 mg/kg Robinin for 10 days |
| Administration: | Oral gavage (p.o.) |
| Result: | Reduced the cardiotoxic effects of Doxorubicin-induced |
