Chemical Properties
white crystalline powder
Originator
Antineuralgiae,Jelfa
Definition
ChEBI: Carbromal is a N-acylurea.
Manufacturing Process
120 parts urea and 258 parts 2-bromo-2-ethylbutyrylbromide was mixed and
stood at room temperature for 12 hours; then the mixture was heated about
3 hours on water bath and adjusted to alkaline pH with sodium bicarbonate
after cooling. The unreacted products was dissolved in brine, the insoluble
part was filtered off. The recrystallization from ethanol gave the title product -
(2-bromo-2-ethyl-butyryl)urea as the colorless, odorless crystals. MP 114°-
118°C.
brand name
Adalin
(Sterling Winthrop).
Therapeutic Function
Hypnotic, Sedative
General Description
Odorless tasteless white crystalline powder. Saturated solution in water neutral to litmus.
Air & Water Reactions
May be sensitive to prolonged exposure to air and light. Insoluble in water.
Reactivity Profile
The neat material may be sensitive to prolonged exposure to air and light. (2-BROMO-2-ETHYLBUTYRYL)UREA is incompatible with acids and alkalis.
Fire Hazard
Flash point data for (2-BROMO-2-ETHYLBUTYRYL)UREA are not available; however, (2-BROMO-2-ETHYLBUTYRYL)UREA is probably combustible.
Safety Profile
Poison by ingestion,
subcutaneous, and possibly other routes.
Moderately toxic via intravenous and
intraperitoneal routes. Mutation data
reported. A sedative, hypnotic, and central Intdious system depressant. When heated
to decomposition it emits very toxic fumes
of NOx and Br-.
