Uses
Galanin (1-13)-spantide I is a chimeric peptide composed of the N-terminal fragment of galanin (amino acids 1-13) and spantide, a known substance P receptor antagonist. Galanin (1-13)-spantide I has a high affinity for spinal galanin receptor (Kd=1.16 nM). Galanin (1-13)-spantide I can be used to study the effects of galanin on feeding behavior[1][2].
References
[1] Crawley J N, et al. Galanin receptor antagonists M40 and C7 block galanin-induced feeding[J]. Brain research, 1993, 600(2): 268-272. DOI:
10.1016/0006-8993(93)91382-3[2] Xu X J, et al. New high affinity peptide antagonists to the spinal galanin receptor[J]. British journal of pharmacology, 1995, 116(3): 2076-2080. DOI:
10.1111/j.1476-5381.1995.tb16414.x
