4-OctylbenzoylaMido-propyl-diMethylaMMoniosulfobetaine

Uses

A Zwitterionic detergent that stabilizes and solubilizes integral membrane proteins by breaking aggregates. Useful for proteins analysis and characterization by 2D-gel electrophoresis and mass spectrometry. Superior to CHAPS in solubilizing both an anion-channel and G-protein coupled receptor.

General Description

A zwitterionic detergent with an aromatic core that is shown to stabilize and solubilize integral membrane proteins by breaking aggregates. Useful for protein analysis and characterization by two-dimensional (2-D) gel electrophoresis and mass spectrometry techniques. Reported to be superior to CHAPS (Cat. No. 220201) in solubilizing both an anion-channel and a G-protein coupled receptor (GPCR).