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PTEROIC ACID

PTEROIC ACID Structure
PTEROIC ACID
  • CAS No.119-24-4
  • Chemical Name:PTEROIC ACID
  • CBNumber:CB8254618
  • Molecular Formula:C14H12N6O3
  • Formula Weight:312.28
  • MOL File:119-24-4.mol
PTEROIC ACID Property
  • Melting point: :>400℃
  • Boiling point: :610.0±65.0 °C(Predicted)
  • Density  :1.69
  • storage temp.  :2-8°C
  • pka :4.65±0.10(Predicted)
  • form  :neat
  • FDA UNII :8258W48TBZ
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
PTEROIC ACID Price More Price(42)
  • Brand: Sigma-Aldrich
  • Product number: P1781
  • Product name : Pteroic acid
  • Purity: ≥93%
  • Packaging: 25mg
  • Price: $64.5
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: P1781
  • Product name : Pteroic acid
  • Purity: ≥93%
  • Packaging: 50mg
  • Price: $104
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: Y0001243
  • Product name : Folic acid impurity D
  • Purity: European Pharmacopoeia (EP) Reference Standard
  • Packaging: 
  • Price: $190
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: PHR2002
  • Product name : Folic Acid Impurity D
  • Purity: Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging: 100 mg
  • Price: $482
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Usbiological
  • Product number: 287467
  • Product name : Pteroic acid
  • Purity: 
  • Packaging: 50mg
  • Price: $433
  • Updated: 2021/12/16
  • Buy: Buy

PTEROIC ACID Chemical Properties,Usage,Production

  • Uses Pteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.
  • Uses Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.
  • General Description
    Folic Acid Impurity D is an impurity of the water-soluble B-vitamin, folic acid. Folic Acid is generally used in the treatment of certain types of anemia.
    Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
  • Enzyme inhibitor This metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.
  • Purification Methods Crystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]
PTEROIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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119-24-4, PTEROIC ACIDRelated Search:
  • 4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid
  • 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
  • 4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
  • 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid
  • 4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoic Acid
  • NSC 14972
  • p-[(2-AMino-4-hydroxy-6-pteridylMethyl)aMino]benzoic Acid
  • Pyrofolic acid
  • Benzoic acid, 4-[[(2-aMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]-
  • 4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid
  • Folic acid iMpurity D
  • Folic acid iMpurity D Pteroic acid
  • Pteroic Acid (>85%)
  • Pteroic acid - min95%
  • Pteroic acid >=93%
  • NSC 14972 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid
  • 4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)
  • PTEROIC ACID
  • p-((2-amino-4-hydroxypteridin-6-yl)methylamino)benzoic acid
  • PTEROIC ACID HYDRATE, 90%
  • Folic acid EP Impurity D
  • Folic Acid Impurity 6
  • Pteroic acid(Instant type)
  • Methotrexate EP Impurity D N-Desmethyl Impurity
  • 4-(((2-amino-4-hydroxypteridin-6-yl)
  • Folic acid impurity D CRS
  • 4-[[(2-Amino-4-oxo-1,4-dihydropteri
  • Pteroic Acid (&gt
  • Methotrexate EP Impurity D Desmethyl Impurity
  • Folic Acid Impurity 6(Folic Acid EP Impurity D)
  • 119-24-4
  • C14H12N6O3
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